Adsorption of human serum albumin onto gold: a combined electrochemical and ellipsometric study
文献类型：期刊论文
| 作者 | Ying PQ(应佩青); Viana AS; Abrantes LM; Jin G(靳刚)
|
| 刊名 | Journal of Colloid and Interface Science
 |
| 出版日期 | 2004 |
| 卷号 | 279期号:1页码:95-99 |
| 通讯作者邮箱 | gajin@imech.ac.cn |
| 关键词 | Human Serum Albumin Adsorption Gold Electrochemistry Ellipsometry Substratum Surface-Properties Protein Adsorption Metal-Surfaces Electrode Reflectometry Fibrinogen Interface Layers |
| ISSN号 | 0021-9797 |
| 通讯作者 | Jin, G (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100080, Peoples R China. |
| 中文摘要 | Human serum albumin adsorption onto gold surfaces was investigated by electrochemical and ellipsometric methods. Albumin adsorption onto gold was confirmed by the change of the open circuit potential of gold and by the ellipsometric parameter variation during albumin immobilization. In both experiments the parameters reached stable values within 10-15 min. The albumin adsorption layer thickness measured with the ellipsometer was about 1.5 nm. The adsorption of albumin Under applied potential was also investigated and it was found that both positive and negative applied potential promote albumin adsorption. Changes in the optical parameters of bare gold and albumin adsorbed onto gold surface under applied potential were investigated with in Situ ellipsometry. The similarity and reversibility of the optical changes showed that adsorbed albumin was stable on the gold surface Under the applied potential range (-200-600 mV). The cyclic voltammograms of K3Fe(CN)(6) on the modified gold surface showed that albumin Could partly block the oxidation and reduction reaction. (C) 2004 Elsevier Inc. All rights reserved. |
| 类目[WOS] | Chemistry, Physical |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | SUBSTRATUM SURFACE-PROPERTIES ; PROTEIN ADSORPTION ; METAL-SURFACES ; ELECTRODE ; REFLECTOMETRY ; FIBRINOGEN ; INTERFACE ; LAYERS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000224708300010 |
| 公开日期 | 2009-08-03 ; 2010-06-13 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/33749]  |
| 专题 | 力学研究所_力学所知识产出(1956-2008) |
| 推荐引用方式 GB/T 7714 | Ying PQ,Viana AS,Abrantes LM,et al. Adsorption of human serum albumin onto gold: a combined electrochemical and ellipsometric study[J]. Journal of Colloid and Interface Science,2004,279(1):95-99. |
| APA | 应佩青,Viana AS,Abrantes LM,&靳刚.(2004).Adsorption of human serum albumin onto gold: a combined electrochemical and ellipsometric study.Journal of Colloid and Interface Science,279(1),95-99. |
| MLA | 应佩青,et al."Adsorption of human serum albumin onto gold: a combined electrochemical and ellipsometric study".Journal of Colloid and Interface Science 279.1(2004):95-99. |
入库方式： OAI收割
来源：力学研究所
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