Evaluation of Cu in hepatocellular carcinoma by particle induced X-ray emission
文献类型：期刊论文
| 作者 | Jin Jie; Shen Hao; Yu Hongxiu; Yao Huiying; Mao Jun; Wang Chenji; Yang Mingjie; Mi Yong |
| 刊名 | JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
 |
| 出版日期 | 2007 |
| 卷号 | 21页码:255-260 |
| 关键词 | copper hepatocellular carcinoma surrounding liver parenchyma particle induced x-ray emission accumulation |
| ISSN号 | 0946-672X |
| DOI | 10.1016/j.jtemb.2007.06.004 |
| 英文摘要 | copper, zinc, iron, and other nine trace elements (TEs) in 30 patients with hepatocellular carcinoma (HCC) were determined from the HCC itself and the surrounding liver parenchyma (SLP) using particle induced X-ray emission (PIXE). The result showed that the level of Zn, Fe, Co, Ca, Mn, Rb, and Cl in HCC significantly differed from that in the SLP (P<0.01), while no notable change has been observed in content of Cu (P = 0.9). However, in relation to tumor size, an imbalance Cu distribution was observed. The content of Cu present in small HCC (< 35 mm in average diameter) was greater than that in SLP (P<0.4), and when HCC progressed to large one (>35mm in average diameter), hepatic Cu was no longer accumulated. Other elements such as Zn and Fe, showed no change in concentration relative to tumor size. The significance of the critical HCC size where a change from accumulation to loss in Cu contents is seen is also discussed. (c) 2007 Elsevier GmbH. All rights reserved. |
| WOS关键词 | COPPER ; LIVER ; METALLOTHIONEIN ; ACCUMULATION ; DIAGNOSIS ; CIRRHOSIS ; CANCERS ; TUMOR ; RATS |
| WOS研究方向 | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 语种 | 英语 |
| WOS记录号 | WOS:000251510000004 |
| 出版者 | ELSEVIER GMBH, URBAN & FISCHER VERLAG |
| 源URL | [http://119.78.100.186/handle/113462/27518]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Shen Hao |
| 作者单位 | 1.Fudan Univ, Inst Modern Phys, Appl Ion Beam Phys Lab, Shanghai 200433, Peoples R China 2.Fudan Univ, Inst Biomed Sci, Shanghai 200433, Peoples R China 3.Fudan Univ, Inst Genet, Shanghai 200433, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin Jie,Shen Hao,Yu Hongxiu,et al. Evaluation of Cu in hepatocellular carcinoma by particle induced X-ray emission[J]. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY,2007,21:255-260. |
| APA | Jin Jie.,Shen Hao.,Yu Hongxiu.,Yao Huiying.,Mao Jun.,...&Mi Yong.(2007).Evaluation of Cu in hepatocellular carcinoma by particle induced X-ray emission.JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY,21,255-260. |
| MLA | Jin Jie,et al."Evaluation of Cu in hepatocellular carcinoma by particle induced X-ray emission".JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY 21(2007):255-260. |
入库方式： OAI收割
来源：近代物理研究所
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