Synergic mechanism and fabrication target for bipedal nanomotors
文献类型：期刊论文
| 作者 | Wang, Zhisong |
| 刊名 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
 |
| 出版日期 | 2007-11-13 |
| 卷号 | 104页码:17921-17926 |
| 关键词 | molecular devices molecular mechanics theory nanotechnology Brownian motor |
| ISSN号 | 0027-8424 |
| DOI | 10.1073/pnas.0703639104 |
| 英文摘要 | Inspired by the discovery of dimeric motor proteins capable of undergoing transportation in living cells, significant efforts have been expended recently to the fabrication of track-walking nanomotors possessing two foot-like components that each can bind or detach from an array of anchorage groups on the track in response to local events of reagent consumption. The central problem in fabricating bipedal nanomotors is how the motor as a whole can gain the synergic capacity of directional track-walking, given the fact that each pedal component alone often is incapable of any directional drift. Implemented bipedal motors to date solve this thermodynamically intricate problem by an intuitive strategy that requires a hetero-pedal motor, multiple anchorage species for the track, and multiple reagent species for motor operation. Here we performed realistic molecular mechanics calculations on molecule-scale models to identify a detailed molecular mechanism by which motor-level directionality arises from a homo-pedal motor along a minimally heterogeneous track. Optimally, the operation may be reduced to a random supply of a single species of reagents to allow the motor's autonomous functioning. The mechanism suggests a distinct class of fabrication targets of drastically reduced system requirements. Intriguingly, a defective form of the mechanism falls into the realm of the well known Brownian motor mechanism, yet distinct features emerge from the normal working of the mechanism. |
| WOS关键词 | MOLECULAR SHUTTLE ; WORMLIKE CHAINS ; BROWNIAN MOTOR ; DNA WALKER ; KINESIN ; PROTEIN ; CLOSURE ; MOTION ; TRACK ; ROTOR |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000251077000007 |
| 出版者 | NATL ACAD SCIENCES |
| 源URL | [http://119.78.100.186/handle/113462/27920]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Wang, Zhisong |
| 作者单位 | Fudan Univ, Inst Modern Phys, Appl Ion Beam Phys Lab, Shanghai 200433, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Zhisong. Synergic mechanism and fabrication target for bipedal nanomotors[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2007,104:17921-17926. |
| APA | Wang, Zhisong.(2007).Synergic mechanism and fabrication target for bipedal nanomotors.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,104,17921-17926. |
| MLA | Wang, Zhisong."Synergic mechanism and fabrication target for bipedal nanomotors".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 104(2007):17921-17926. |
入库方式： OAI收割
来源：近代物理研究所
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