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EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY

文献类型：期刊论文

作者Wang, S. Y.1,2; Liang, J. P.3; Song, N. N.4; Shao, W. J.1; Heng, H.1
刊名JOURNAL OF CAMEL PRACTICE AND RESEARCH
出版日期2009-06-01
卷号16页码:107-113
关键词Animals models camel milk glycaemia control Rosiglitazone Maleate Type 2 diabetes
ISSN号0971-6777
英文摘要The efficacy of camel milk consumption as an adjunct to routine diabetes management in maintaining long-term glycaemia control in type 2 diabetes was assessed by 32 type 2 diabetes animal models and 12 patients. Thirty-two obese diabetic rats were divided into 4 groups according to method of random digits table. After 14 weeks treatment, it was observed that no significant variance compared Rosiglitazone Maleate group, Rosiglitazone Maleate+camel milk group and camel milk group with normal group. In blood glucose, blood triglycerides, blood total cholesterol, and plasma insulin there were a statistically significant change compared with diabetes group. Rosiglitazone Maleate group and Rosiglitazone Maleate+camel milk group showed significant variance in blood triglycerides (0.68+/-0.19 vs. 0.51+/-0.11 p<0.05), plasma insulin (43.52+/-18.93 vs. 26.49+/-5.60 p<0.05). Rosiglitazone Maleate+calnel milk group was more similar to normal group. Rosiglitazone Maleate+camel milk group had better treatment of type 2 diabetes animal models than Rosiglitazone Maleate group. Throughout the duration of the study, 6 randomly assigned patients underwent routine diabetes management and 6 randomly assigned patients additionally undertook daily consumption of raw camel milk (500 ml/day). In both groups, the dose of potential Rosiglitazone Maleate administration was adjusted to maintain a euglycaemic. In the group receiving camel milk, there was a significant increase in body weight (74.6+/-5.2 to 78.3+/-3.4; p<0.05) and a significant reduction in mean blood sugar (123+/-19.8 to 94.2+/-14.3; p<0.001), plasma insulin (19.76+/-2.3 to 6.2+/-0.56; p<0.001), dose of drug (4.67+/-0.91 to 1.67+/-1.3; p<0.001), blood triglycerides (1.83+/- 0.38 to 1.42+/-0.94; p<0.001), blood total cholesterol (7.7+/-1.53 to 6.1+/-0.91; p<0.001) compared to the values at the initiation of the study. Based on the results, camel milk consumption may be considered as a useful prevention and adjunct to potential Rosiglitazone Maleate administration in the management of type 2 diabetes.
WOS关键词QUALITY-OF-LIFE ; GLYCEMIC CONTROL ; FATTY-ACIDS ; INSULIN ; DROMEDARY ; COLOSTRUM ; DIET ; RISK
资助项目Gansu Hualong Agricultural Development Corporation
WOS研究方向Veterinary Sciences
语种英语
WOS记录号WOS:000272063900019
出版者CAMEL PUBL HOUSE
资助机构Gansu Hualong Agricultural Development Corporation
源URL[http://119.78.100.186/handle/113462/30346]  
专题中国科学院近代物理研究所
通讯作者Wang, S. Y.
作者单位1.Gansu Agr Univ, Dept Anim Med, Lanzhou 730070, Peoples R China
2.Chinese Acad Sci, Inst Modern Phys, Dept Biol Phys, Lanzhou 730000, Peoples R China
3.Chinese Acad Agr Sci, Lanzhou Inst Anim & Vet Pharmaceut Sci, Lanzhou 730050, Peoples R China
4.Lanzhou Univ, Dept Med, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714		 Wang, S. Y.,Liang, J. P.,Song, N. N.,et al. EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY[J]. JOURNAL OF CAMEL PRACTICE AND RESEARCH,2009,16:107-113.
APA Wang, S. Y.,Liang, J. P.,Song, N. N.,Shao, W. J.,&Heng, H..(2009).EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY.JOURNAL OF CAMEL PRACTICE AND RESEARCH,16,107-113.
MLA Wang, S. Y.,et al."EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY".JOURNAL OF CAMEL PRACTICE AND RESEARCH 16(2009):107-113.

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来源：近代物理研究所

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