The effects of strontium ranelate treatment on ovariectomized Sprague-Dawley rat tibia
文献类型：期刊论文
| 作者 | Zheng, Y.1; Jin, W.2; Wang, C.1; Yang, M.1; Shen, H.1; Eisa, M. H.3; Mi, Y.1 |
| 刊名 | NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS
 |
| 出版日期 | 2009-06-15 |
| 卷号 | 267页码:2128-2131 |
| 关键词 | Micro-PIXE Osteoporosis Ovariectomized Strontium ranelate |
| ISSN号 | 0168-583X |
| DOI | 10.1016/j.nimb.2009.03.066 |
| 英文摘要 | Micro Proton Induced X-ray Emission (micro-PIXE) technique was used to study the effect of strontium ranelate on osteoporosis resulted from estrogen deficiency. The contents of calcium and strontium in tibia, as well as calcium distribution for structural determination were investigated. Three groups of tibia samples were respectively taken from three groups of female Sprague-Dawley (S.D.) rats, i.e. control, ovariectomized and ovariectomized followed strontium ranelate treatment. It was found that the strontium content was decreasing in the bone from ovariectomized rat compared with that in control, but significantly increasing in the bone from strontium ranelate treated ovariectomized rat. Our study showed that strontium content is a feasible parameter for the diagnosis of osteoporosis caused by estrogen deficiency. Strontium ranelate is an effective antiosteoporosis chemical to rebuild the bone structure and prevent deterioration of bone strength as well. (C) 2009 Elsevier B.V. All rights reserved. |
| WOS关键词 | BONE MICROARCHITECTURE ; OSTEOPOROSIS ; MICROPROBE ; PIXE ; ARCHITECTURE ; FRACTURE ; SAMPLES ; FEMUR ; WOMEN ; RISK |
| WOS研究方向 | Instruments & Instrumentation ; Nuclear Science & Technology ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000267910500032 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://119.78.100.186/handle/113462/30514]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Shen, H. |
| 作者单位 | 1.Fudan Univ, Inst Modern Phys, Shanghai 200433, Peoples R China 2.Fudan Univ, Inst Radiat Med, Shanghai 200032, Peoples R China 3.Sudan Univ Sci & Technol, Dept Phys, Coll Sci, Khartoum 111113, Sudan |
| 推荐引用方式 GB/T 7714 | Zheng, Y.,Jin, W.,Wang, C.,et al. The effects of strontium ranelate treatment on ovariectomized Sprague-Dawley rat tibia[J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,2009,267:2128-2131. |
| APA | Zheng, Y..,Jin, W..,Wang, C..,Yang, M..,Shen, H..,...&Mi, Y..(2009).The effects of strontium ranelate treatment on ovariectomized Sprague-Dawley rat tibia.NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,267,2128-2131. |
| MLA | Zheng, Y.,et al."The effects of strontium ranelate treatment on ovariectomized Sprague-Dawley rat tibia".NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS 267(2009):2128-2131. |
入库方式： OAI收割
来源：近代物理研究所
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