Acylphloroglucinol derivatives from Decaspermum gracilentum and their antiradical and cytotoxic activities
文献类型：期刊论文
| 作者 | Sun, Meng1; Gobu, Fekadu-Roge1; Pan, Dong2,3; Li, Ya1; Gao, Kun1 |
| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2016-01-02 |
| 卷号 | 18页码:13-19 |
| 关键词 | acylphloroglucinol derivatives Myrtaceae cytotoxic activity Decaspermum gracilentum radical scavenging activity |
| ISSN号 | 1028-6020 |
| DOI | 10.1080/10286020.2015.1119129 |
| 英文摘要 | Two new acylphloroglucinol derivatives, 1-(hexanoyl)phloroglucinol-alpha-d-arabinopyranoside (1) and 1-(hexanoyl)phloroglucinol-beta-d-glucopyranoside (2), along with two known ones, 1-(acetyl)phloroglucinol-beta-d-glucopyranoside (3) and ethyl 2,4,6-trihydroxybenzoate (4), were isolated from the EtOAc soluble fraction of EtOH extract of Decaspermum gracilentum. The structures of the new compounds were determined by extensive spectroscopic analyses including HRESIMS, 1D and 2D NMR data. Interestingly, all of the compounds showed ABTS(center dot+) radical scavenging activity with the IC50 values less than 10 mu M. Furthermore, compounds 3 and 4 displayed moderate cytotoxicity on human non-small-cell lung carcinoma cell line A549 (IC50=50.9 mu M) and human renal carcinoma cell line 786-O (IC50=38.6 mu M), respectively. |
| WOS关键词 | ANTIOXIDANT ACTIVITY |
| 资助项目 | National Basic Research Program (973) of China[2014CB138703] ; National Natural Science Foundation of China[31270396] ; National Natural Science Foundation of China[21402074] |
| WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000371017700002 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 资助机构 | National Basic Research Program (973) of China ; National Natural Science Foundation of China |
| 源URL | [http://119.78.100.186/handle/113462/41966]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Gao, Kun |
| 作者单位 | 1.Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Inst Modern Phys, Gansu Key Lab Space Radiobiol, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Meng,Gobu, Fekadu-Roge,Pan, Dong,et al. Acylphloroglucinol derivatives from Decaspermum gracilentum and their antiradical and cytotoxic activities[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2016,18:13-19. |
| APA | Sun, Meng,Gobu, Fekadu-Roge,Pan, Dong,Li, Ya,&Gao, Kun.(2016).Acylphloroglucinol derivatives from Decaspermum gracilentum and their antiradical and cytotoxic activities.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,18,13-19. |
| MLA | Sun, Meng,et al."Acylphloroglucinol derivatives from Decaspermum gracilentum and their antiradical and cytotoxic activities".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 18(2016):13-19. |
入库方式： OAI收割
来源：近代物理研究所
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