Influences of pH and Iron Concentration on the Salivary Microbiome in Individual Humans with and without Caries
文献类型：期刊论文
| 作者 | Zhou, Jianye1; Jiang, Nan2; Wang, Zhenzhen3; Li, Longqing4; Zhang, Jumei1; Ma, Rui3; Nie, Hongbing1; Li, Zhiqiang1 |
| 刊名 | APPLIED AND ENVIRONMENTAL MICROBIOLOGY
 |
| 出版日期 | 2017-02-01 |
| 卷号 | 83页码:12 |
| 关键词 | caries iron microbial communities pH saliva |
| ISSN号 | 0099-2240 |
| DOI | 10.1128/AEM.02412-16 |
| 英文摘要 | This study aimed to identify the differences in the oral microbial communities in saliva from patients with and without caries by performing sequencing with the Illumina MiSeq platform, as well as to further assess their relationships with environmental factors (salivary pH and iron concentration). Forty-three volunteers were selected, including 21 subjects with and 22 without caries, from one village in Gansu, China. Based on 966,255 trimmed sequences and clustering at the 97% similarity level, 1,303 species-level operational taxonomic units were generated. The sequencing data for the two groups revealed that (i) particular distribution patterns (synergistic effects or competition) existed in the subjects with and without caries at both the genus and species levels and (ii) both the salivary pH and iron concentration had significant influences on the microbial community structure. IMPORTANCE The significant influences of the oral environment observed in this study increase the current understanding of the salivary microbiome in caries. These results will be useful for expanding research directions and for improving disease diagnosis, prognosis, and therapy. |
| WOS关键词 | IN-VITRO ; DENTAL-CARIES ; ENAMEL DEMINERALIZATION ; SUBGINGIVAL MICROBIOTA ; ACID DEMINERALIZATION ; COMMUNITY COMPOSITION ; BOVINE ENAMEL ; BIOFILM ; BACTERIA ; HEALTH |
| 资助项目 | National Natural Science Fund[31360124/C0309] ; National Natural Science Fund[31560159/C0309] ; Special International Technology Cooperation of Gansu Province[144WCGA167] |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000393482200002 |
| 出版者 | AMER SOC MICROBIOLOGY |
| 资助机构 | National Natural Science Fund ; Special International Technology Cooperation of Gansu Province |
| 源URL | [http://119.78.100.186/handle/113462/44304]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Li, Zhiqiang |
| 作者单位 | 1.Northwest Univ Nationalities, Key Lab Oral Dis Gansu Prov, Key Lab Stomatol State Ethn Affairs Commiss, Lanzhou, Gansu, Peoples R China 2.Chinese Acad Sci, Inst Appl Ecol, Shenyang, Peoples R China 3.Lanzhou Univ, Sch Stomatol, Lanzhou, Peoples R China 4.Chinese Acad Sci, Inst Modern Phys, Lanzhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Jianye,Jiang, Nan,Wang, Zhenzhen,et al. Influences of pH and Iron Concentration on the Salivary Microbiome in Individual Humans with and without Caries[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY,2017,83:12. |
| APA | Zhou, Jianye.,Jiang, Nan.,Wang, Zhenzhen.,Li, Longqing.,Zhang, Jumei.,...&Li, Zhiqiang.(2017).Influences of pH and Iron Concentration on the Salivary Microbiome in Individual Humans with and without Caries.APPLIED AND ENVIRONMENTAL MICROBIOLOGY,83,12. |
| MLA | Zhou, Jianye,et al."Influences of pH and Iron Concentration on the Salivary Microbiome in Individual Humans with and without Caries".APPLIED AND ENVIRONMENTAL MICROBIOLOGY 83(2017):12. |
入库方式： OAI收割
来源：近代物理研究所
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