The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines
文献类型:期刊论文
作者 | Zhao, Jin1; Guo, Zhong1; Zhang, Hong2![]() |
刊名 | RADIOLOGY AND ONCOLOGY
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出版日期 | 2013-09-01 |
卷号 | 47页码:247-257 |
关键词 | Human Tumour Cells Carbon Ions X-rays Radiation Sensitivity Dna Double Strand Breaks Gamma H2ax |
ISSN号 | 1318-2099 |
DOI | 10.2478/raon-2013-0045 |
文献子类 | Article |
英文摘要 | Background. Carbon ions (C-12(6+)) are high linear energy transfer (LET) radiation characterized by higher relative biological effectiveness than low LET radiation. The assessment of tumour radiosensitivity would be particularly useful in optimizing the radiation dose during radiotherapy. The aim of the current study was to evaluate the potential value of the neutral comet assay and gamma H2AX foci assay in assessing C-12(6+) radiosensitivity of tumour cells. |
WOS关键词 | DOUBLE-STRAND BREAKS ; CLUSTERED DNA LESIONS ; HIGH-LET ; HUMAN FIBROBLASTS ; MAMMALIAN-CELLS ; RADIATION ; DAMAGE ; REPAIR ; IRRADIATION ; IONS |
资助项目 | Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry[[2011]1568] |
WOS研究方向 | Oncology ; Radiology, Nuclear Medicine & Medical Imaging |
语种 | 英语 |
WOS记录号 | WOS:000322968000008 |
出版者 | ASSOC RADIOLOGY & ONCOLOGY |
源URL | [http://119.78.100.186/handle/113462/48181] ![]() |
专题 | 中国科学院近代物理研究所 |
通讯作者 | Zhao, Jin |
作者单位 | 1.Northwest Univ Nationalities, Coll Med, Lanzhou 730030, Peoples R China 2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China 3.Yantai Univ, Sch Life Sci, Yantai 264005, Peoples R China |
推荐引用方式 GB/T 7714 | Zhao, Jin,Guo, Zhong,Zhang, Hong,et al. The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines[J]. RADIOLOGY AND ONCOLOGY,2013,47:247-257. |
APA | Zhao, Jin.,Guo, Zhong.,Zhang, Hong.,Wang, Zhenhua.,Song, Lei.,...&Wang, Chenjing.(2013).The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines.RADIOLOGY AND ONCOLOGY,47,247-257. |
MLA | Zhao, Jin,et al."The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines".RADIOLOGY AND ONCOLOGY 47(2013):247-257. |
入库方式: OAI收割
来源:近代物理研究所
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