中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines

文献类型:期刊论文

作者Zhao, Jin1; Guo, Zhong1; Zhang, Hong2; Wang, Zhenhua3; Song, Lei1; Ma, Jianxiu1; Pei, Shuyan1; Wang, Chenjing1
刊名RADIOLOGY AND ONCOLOGY
出版日期2013-09-01
卷号47页码:247-257
关键词Human Tumour Cells Carbon Ions X-rays Radiation Sensitivity Dna Double Strand Breaks Gamma H2ax
ISSN号1318-2099
DOI10.2478/raon-2013-0045
文献子类Article
英文摘要Background. Carbon ions (C-12(6+)) are high linear energy transfer (LET) radiation characterized by higher relative biological effectiveness than low LET radiation. The assessment of tumour radiosensitivity would be particularly useful in optimizing the radiation dose during radiotherapy. The aim of the current study was to evaluate the potential value of the neutral comet assay and gamma H2AX foci assay in assessing C-12(6+) radiosensitivity of tumour cells.
WOS关键词DOUBLE-STRAND BREAKS ; CLUSTERED DNA LESIONS ; HIGH-LET ; HUMAN FIBROBLASTS ; MAMMALIAN-CELLS ; RADIATION ; DAMAGE ; REPAIR ; IRRADIATION ; IONS
资助项目Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry[[2011]1568]
WOS研究方向Oncology ; Radiology, Nuclear Medicine & Medical Imaging
语种英语
WOS记录号WOS:000322968000008
出版者ASSOC RADIOLOGY & ONCOLOGY
源URL[http://119.78.100.186/handle/113462/48181]  
专题中国科学院近代物理研究所
通讯作者Zhao, Jin
作者单位1.Northwest Univ Nationalities, Coll Med, Lanzhou 730030, Peoples R China
2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China
3.Yantai Univ, Sch Life Sci, Yantai 264005, Peoples R China
推荐引用方式
GB/T 7714
Zhao, Jin,Guo, Zhong,Zhang, Hong,et al. The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines[J]. RADIOLOGY AND ONCOLOGY,2013,47:247-257.
APA Zhao, Jin.,Guo, Zhong.,Zhang, Hong.,Wang, Zhenhua.,Song, Lei.,...&Wang, Chenjing.(2013).The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines.RADIOLOGY AND ONCOLOGY,47,247-257.
MLA Zhao, Jin,et al."The potential value of the neutral comet assay and gamma H2AX foci assay in assessing the radiosensitivity of carbon beam in human tumor cell lines".RADIOLOGY AND ONCOLOGY 47(2013):247-257.

入库方式: OAI收割

来源:近代物理研究所

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