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Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation-Induced Emission

文献类型:期刊论文

作者Xue, Xiangdong1; Zhao, Yuanyuan1; Dai, Luru1; Zhang, Xu1; Hao, Xiaohong1; Zhang, Chunqiu1; Huo, Shuaidong1; Liu, Juan1; Liu, Chang2; Kumar, Anil1
刊名ADVANCED MATERIALS
出版日期2014-02-05
卷号26页码:712-717
ISSN号0935-9648
DOI10.1002/adma.201302365
文献子类Article
英文摘要Tetraphenylethene and doxorubicin are assembled into a self-indicating drug delivery system (TD NPs). TD NPs are decomposed into DOX and TPE NPs in lysosome. Since TD NPs, TPE NPs and DOX are all fluorescent, the detachment of DOX from TPE NPs is accompanied by fluorescence changing. By observing the fluorescence changes, the spatiotemporal drug release is visualized.
WOS关键词IN-VITRO ; FLUORESCENT BIOPROBES ; QUANTUM DOTS ; NANOPARTICLES ; CYTOTOXICITY ; VIVO ; TETRAPHENYLETHENE ; NANOCARRIERS ; GLUTATHIONE ; PLATFORM
资助项目Chinese Academy of Sciences (CAS) "Hundred Talents Program"[07165111ZX]
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
语种英语
WOS记录号WOS:000336043500005
出版者WILEY-V C H VERLAG GMBH
源URL[http://119.78.100.186/handle/113462/49897]  
专题中国科学院近代物理研究所
通讯作者Zou, Guozhang
作者单位1.Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
2.Beijing Univ Technol, Beijing 100022, Peoples R China
3.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714
Xue, Xiangdong,Zhao, Yuanyuan,Dai, Luru,et al. Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation-Induced Emission[J]. ADVANCED MATERIALS,2014,26:712-717.
APA Xue, Xiangdong.,Zhao, Yuanyuan.,Dai, Luru.,Zhang, Xu.,Hao, Xiaohong.,...&Liang, Xing-Jie.(2014).Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation-Induced Emission.ADVANCED MATERIALS,26,712-717.
MLA Xue, Xiangdong,et al."Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation-Induced Emission".ADVANCED MATERIALS 26(2014):712-717.

入库方式: OAI收割

来源:近代物理研究所

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