Treatment planning for scanned ion beams
文献类型：会议论文
| 作者 | Haberer, T; Kramer, M; Jakel, O; Rietzel, E; Schardt, D; Scholz, M; Wang, JF; Weber, U; Weyrather, W |
| 出版日期 | 2004-12 |
| 关键词 | scanned ion beams treatment planning radiotherapy |
| 卷号 | 73 |
| 页码 | S80-S85 |
| 英文摘要 | Since 1997 a radiotherapy unit using fast carbon ions is operational at GSI. An intensity-controlled magnetic raster scanner together with a synchrotron allowing fast energy variation enable a unique method of purely active dose shaping in three dimensions. This contribution describes the necessary steps to establish a treatment planning system for this novel modality. We discuss the requirements for the physical beam model and the radiobiological model. Based on these we chose to implement a home-grown pencil beam model to describe the ion-tissue interaction and the Local Effect Model to calculate the RBE voxel-by-voxel. Given the large number of degrees of freedom biological dose optimization must be achieved by means of inverse treatment planning. All ion-related aspects are collected in our TRiP98 software. Biological dosimetry measuring cell survival in two dimensions turns out to be a good way to verify the model predictions as well as the actual irradiation procedure. We show a patient example and outline the future steps towards a dedicated clinic facility for all light ions. |
| 会议录 | RADIOTHERAPY AND ONCOLOGY
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| 会议录出版者 | ELSEVIER SCI IRELAND LTD |
| 会议录出版地 | CUSTOMER RELATIONS MANAGER, BAY 15, SHANNON INDUSTRIAL ESTATE CO, CLARE, IRELAND |
| 语种 | 英语 |
| WOS研究方向 | Oncology ; Radiology, Nuclear Medicine & Medical Imaging |
| WOS记录号 | WOS:000227647500021 |
| 源URL | [http://119.78.100.186/handle/113462/58283]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Kramer, M |
| 作者单位 | 1.GSI Biophys, D-64291 Darmstadt, Germany 2.DKFZ, D-69120 Heidelberg, Germany 3.IMP, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Haberer, T,Kramer, M,Jakel, O,et al. Treatment planning for scanned ion beams[C]. 见:. |
入库方式： OAI收割
来源：近代物理研究所
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