中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A preliminary Monte Carlo study for the treatment head of a carbon-ion radiotherapy facility using TOPAS

文献类型:会议论文

作者Liu, Hongdong1; Zhang, Lian1; Chen, Zhi1; Liu, Xinguo2; Dai, Zhongying2; Li, Qiang2; Xu, Xie George1,3; Malvagi, F; Malouch, F; Diop, CMB
出版日期2017
卷号153
DOI10.1051/epjconf/201715304018
英文摘要In medical physics it is desirable to have a Monte Carlo code that is less complex, reliable yet flexible for dose verification, optimization, and component design. TOPAS is a newly developed Monte Carlo simulation tool which combines extensive radiation physics libraries available in Geant4 code, easy-to-use geometry and support for visualization. Although TOPAS has been widely tested and verified in simulations of proton therapy, there has been no reported application for carbon ion therapy. To evaluate the feasibility and accuracy of TOPAS simulations for carbon ion therapy, a licensed TOPAS code (version 3Op1) was used to carry out a dosimetric study of therapeutic carbon ions. Results of depth dose profile based on different physics models have been obtained and compared with the measurements. It is found that the G4QMD model is at least as accurate as the TOPAS default BIC physics model for carbon ions, but when the energy is increased to relatively high levels such as 400 MeV/u, the G4QMD model shows preferable performance. Also, simulations of special components used in the treatment head at the Institute of Modern Physics facility was conducted to investigate the Spread-Out dose distribution in water. The physical dose in water of SOBP was found to be consistent with the aim of the 6 cm ridge filter.
会议录ICRS-13 & RPSD-2016, 13TH INTERNATIONAL CONFERENCE ON RADIATION SHIELDING & 19TH TOPICAL MEETING OF THE RADIATION PROTECTION AND SHIELDING DIVISION OF THE AMERICAN NUCLEAR SOCIETY - 2016
会议录出版者E D P SCIENCES
会议录出版地17 AVE DU HOGGAR PARC D ACTIVITES COUTABOEUF BP 112, F-91944 CEDEX A, FRANCE
语种英语
资助项目NSFC (Natural Science Foundation of China)[11575180]
WOS研究方向Nuclear Science & Technology ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号WOS:000426429200073
源URL[http://119.78.100.186/handle/113462/58367]  
专题中国科学院近代物理研究所
通讯作者Xu, Xie George
作者单位1.Univ Sci & Technol China Hefei, Sch Nucl Sci & Technol, Hefei 230027, Anhui, Peoples R China
2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Gansu, Peoples R China
3.Rensselaer Polytech Inst, Troy, NY 12180 USA
推荐引用方式
GB/T 7714
Liu, Hongdong,Zhang, Lian,Chen, Zhi,et al. A preliminary Monte Carlo study for the treatment head of a carbon-ion radiotherapy facility using TOPAS[C]. 见:.

入库方式: OAI收割

来源:近代物理研究所

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