A novel pencil beam model for carbon-ion dose calculation derived from Monte Carlo simulations
文献类型：期刊论文
| 作者 | Zhang, Hui; Dai, Zhongying ; Liu, Xinguo; Chen, Weiqiang; Ma, Yuanyuan; He, Pengbo; Dai, Tianyuan; Shen, Guosheng; Yuan, Ping; Li, Qiang
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| 刊名 | PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
 |
| 出版日期 | 2018 |
| 卷号 | 55页码:15-24 |
| 关键词 | Heavy ion therapy Kernel beam model Secondary particles Low dose envelope |
| ISSN号 | 1120-1797 |
| DOI | 10.1016/j.ejmp.2018.10.014 |
| 英文摘要 | An accurate kernel model is of vital importance for pencil-beam dose algorithm in charged particle therapy using precise spot-scanning beam delivery, in which an accurate depiction of the low dose envelope is especially crucial. Based on the Monte Carlo method, we investigated the dose contribution of secondary particles to the total dose and proposed a novel beam model to depict the lateral dose distribution of carbon-ion pencil beam in water. We demonstrated that the low dose envelope in single-spot profiles in water could be adequately modelled with the addition of a logistic distribution to a double Gaussian one, which was verified in both single carbon-ion pencil beam and superposed fields of different sizes with multiple pencil beams. Its superiority was mainly manifested at medium depths especially for high-energy beams with small fields compared with single, double and triple Gaussian models, where the secondary particles influenced the total dose considerably. The double Gaussian-logistic model could reduce the deviations from 4.1%, 1.7% to 0.3% in the plateau and peak regions, and from 19.2%, 4.9% to 1.2% in the tail region compared for the field size factor (FSF) calculations of 344 MeV/u carbon-ion pencil beam with the single and double Gaussian models. Compared with the triple Gaussian one, our newly-proposed model was on a par with it, even better than it in the plateau and peak regions. Thus our work will be helpful for improving the dose calculation accuracy for carbon-ion therapy. |
| WOS关键词 | PROTON THERAPY ; SCANNED PROTON ; RADIOTHERAPY ; ALGORITHM ; INSTITUTE ; PROFILES ; SYSTEM ; GATE |
| 资助项目 | Youth Innovation Promotion Association of the Chinese Academy of Sciences[2015340] ; Youth Innovation Promotion Association of the Chinese Academy of Sciences[2017454] |
| WOS研究方向 | Radiology, Nuclear Medicine & Medical Imaging |
| 语种 | 英语 |
| WOS记录号 | WOS:000450741900003 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://119.78.100.186/handle/113462/59884]  |
| 专题 | 近代物理研究所_兰州重离子研究装置 近代物理研究所_生物物理研究室 中国科学院近代物理研究所 |
| 通讯作者 | Li, Qiang |
| 作者单位 | Chinese Acad Sci, Inst Modern Phys, 509 Nanchang Rd, Lanzhou 73000, Gansu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Hui,Dai, Zhongying,Liu, Xinguo,et al. A novel pencil beam model for carbon-ion dose calculation derived from Monte Carlo simulations[J]. PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS,2018,55:15-24. |
| APA | Zhang, Hui.,Dai, Zhongying.,Liu, Xinguo.,Chen, Weiqiang.,Ma, Yuanyuan.,...&Li, Qiang.(2018).A novel pencil beam model for carbon-ion dose calculation derived from Monte Carlo simulations.PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS,55,15-24. |
| MLA | Zhang, Hui,et al."A novel pencil beam model for carbon-ion dose calculation derived from Monte Carlo simulations".PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS 55(2018):15-24. |
入库方式： OAI收割
来源：近代物理研究所
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