Measurement of lineal energy spectra at different penetration depths along a radioactive 9C-ion beam
文献类型：期刊论文
| 作者 | Li, Qiang ; Matsufuji, N.; Urakabe, E.; Kanazawa, M.; Sato, S.
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| 刊名 | Kao Neng Wu Li Yu Ho Wu Li/High Energy Physics and Nuclear Physics
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| 出版日期 | 2005 |
| 卷号 | 29页码:1041-1046 |
| ISSN号 | 0254-3052 |
| 英文摘要 | It is expected that a radioactive 9C-ion beam as a type of double irradiation source can increase the curative effect when applying it to heavy-ion cancer therapy, and it has been proved in our previous radiobiological experiment that the relative biological effectiveness (RBE) at the depths around the Bragg peak of a 9C beam was greater than that of a therapeutic 12C beam at least by a factor of 2. To characterize the physical basis of a 9C ion beam applying to radiotherapy, a spherical tissue-equivalent proportional counter (TEPC) was used to measure the lineal energy (y) spectra at different depths along a radioactive 9C-ion beam in this work. Based on the measured spectra, the distribution of dose-averaged lineal energy in depth was derived. Moreover, the measured lineal energy spectra were converted into the distributions of LET in absorbed dose at the different depths. The distribution of dose-averaged LET in depth, therefore, has been obtained for the 9C beam. The dose-averaged LETs measured with the TEPC and our preceding parallel-plate proportional counter (PPPC) were compared. It has been found that both the measurements agreed well with each other at the entrance channel of the 9C beam while the dose-averaged LETs by the TEPC were larger than those by the PPPC around the Bragg peak, i.e. the stopping region of the incident 9C ions. This coincides with the expectation that all of the delayed alpha particles and protons, which are emitted isotropically during the decays of the 9C ions, can be included by means of the TEPC measurement. The data sets obtained in this work provide a substantial physical basis for revealing the advantages of 9C beams in cancer therapy. |
| 出版者 | Science Press, Beijing, China |
| 源URL | [http://119.78.100.186/handle/113462/64215]  |
| 专题 | 中国科学院近代物理研究所 |
| 作者单位 | 1.Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China 2.National Institute of Radiological Sciences, Chiba 263-8555, Japan |
| 推荐引用方式 GB/T 7714 | Li, Qiang,Matsufuji, N.,Urakabe, E.,et al. Measurement of lineal energy spectra at different penetration depths along a radioactive 9C-ion beam[J]. Kao Neng Wu Li Yu Ho Wu Li/High Energy Physics and Nuclear Physics,2005,29:1041-1046. |
| APA | Li, Qiang,Matsufuji, N.,Urakabe, E.,Kanazawa, M.,&Sato, S..(2005).Measurement of lineal energy spectra at different penetration depths along a radioactive 9C-ion beam.Kao Neng Wu Li Yu Ho Wu Li/High Energy Physics and Nuclear Physics,29,1041-1046. |
| MLA | Li, Qiang,et al."Measurement of lineal energy spectra at different penetration depths along a radioactive 9C-ion beam".Kao Neng Wu Li Yu Ho Wu Li/High Energy Physics and Nuclear Physics 29(2005):1041-1046. |
入库方式： OAI收割
来源：近代物理研究所
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