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Predict of radiosensitivity of human hepatoma cells irradiated with γ-rays by G2 PCC technique

文献类型：期刊论文

作者Yang, Jianshe; Zhao, Jing; Li, Wenjian; Gao, Qingxiang; Wang, Zhuanzi
刊名He Jishu/Nuclear Techniques
出版日期2005
卷号28页码:850-853
ISSN号0253-3219
英文摘要To investigate the radiation response of hepatoma cells SMMC-7721 the G2 premature chromosome condensation technique was used. SMMC-7721 cells (human hepatoma cells) were irradiated with 60Co γ-rays. Then cell killing was documented by a colony assay. Initial chromatid breaks were measured by counting the number of chromatid breaks and isochromatid breaks immediately after prematurely chromosome condensed by Calyculin-A. A dose-dependent increase in radiation-induced chromatid/isochromatid breaks was observed in G2 phase. A good relationship was found between cell survival and chromatid breaks. This study implied that low LET radiation-induced chromatid/isochromatid breaks can be possibly used as a good predictor of radiosensitivity of SMMC-7721 hepatoma cells, also it could be used to design radiotherapy schedule for liver cancer patients.
出版者Science Press, Beijing, China
源URL[http://119.78.100.186/handle/113462/64257]  
专题中国科学院近代物理研究所
作者单位1.Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China
2.Graduate School, Chinese Academy of Sciences, Beijing 100049, China
3.Life School, Lanzhou University, Lanzhou 730000, China
推荐引用方式
GB/T 7714		 Yang, Jianshe,Zhao, Jing,Li, Wenjian,et al. Predict of radiosensitivity of human hepatoma cells irradiated with γ-rays by G2 PCC technique[J]. He Jishu/Nuclear Techniques,2005,28:850-853.
APA Yang, Jianshe,Zhao, Jing,Li, Wenjian,Gao, Qingxiang,&Wang, Zhuanzi.(2005).Predict of radiosensitivity of human hepatoma cells irradiated with γ-rays by G2 PCC technique.He Jishu/Nuclear Techniques,28,850-853.
MLA Yang, Jianshe,et al."Predict of radiosensitivity of human hepatoma cells irradiated with γ-rays by G2 PCC technique".He Jishu/Nuclear Techniques 28(2005):850-853.

入库方式： OAI收割

来源：近代物理研究所

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