Technical Note: Effect of magnetic fields on the microdosimetry of carbon-ion beams
文献类型：期刊论文
| 作者 | Shen, Guosheng ; Dai, Tianyuan; Li, Qiang1; Liu, Xinguo; Dai, Zhongying; He, Pengbo; Ma, Yuanyuan; Chen, Weiqiang; Zhang, Hui; Meng, Qianqian
|
| 刊名 | MEDICAL PHYSICS
 |
| 出版日期 | 2019-08-01 |
| 卷号 | 46期号:8页码:3746-3750 |
| ISSN号 | 0094-2405 |
| 关键词 | carbon-ion therapy magnetic fields microdosimetry MRI image-guided radiotherapy tissue equivalent proportional counter |
| DOI | 10.1002/mp.13633 |
| 通讯作者 | Li, Qiang(liqiang@impcas.ac.cn) |
| 英文摘要 | Purpose To investigate the influence of magnetic fields on the microdosimetry of carbon-ion beams and the scaling effect of tissue equivalent proportional counter (TEPC) defined as the change of energy deposition in a TEPC from that in a microscopic scale region of interest due to the presence of a magnetic field in combination with the TEPC larger physical dimensions. Methods Geant4-based Monte Carlo simulations were conducted to calculate the microdosimetric quantities for carbon-ion beams with different initial energies (10-290 MeV/u) under magnetic fields of various strengths (0.5-3 T). The calculations were performed for a 1 mu m spherical volume made of tissue, and for spherical TEPCs of 1 and 10 mm in diameter. Then, values of dose-averaged lineal energy (y(D)) were acquired for the different scenarios to analyze the effect of magnetic fields on the microdosimetry of carbon-ion beams and the scaling effect of TEPC. Results The y(D) values and lineal energy spectra in the 1 mu m spherical tissue volume for the scenarios without magnetic field and with magnetic fields of different strengths and directions remained nearly the same for the various energy carbon-ion beams. However, compared with those of the 1 mu m spherical tissue volume, an increase of of y(D) values and an obvious shift of the lineal energy spectra for the TEPCs of 1 and 10 mm in diameter under magnetic fields were found. Conclusions The application of magnetic fields under 3 T has no significant influence on the microdosimetric results of carbon-ion beams. However, there is definitely a scaling effect when using TEPC for microdosimetric study, which alters the reading of TEPC in the presence of magnetic fields. Novel methods to correct the reading of TEPC or scaling effect-resistant microdosimetric measurement detectors are urgently needed to perform experimental microdosimetric studies under magnetic fields. |
| WOS关键词 | DOSIMETRY ; GATE |
| WOS研究方向 | Radiology, Nuclear Medicine & Medical Imaging |
| 语种 | 英语 |
| 出版者 | WILEY |
| WOS记录号 | WOS:000482075000040 |
| 源URL | [http://119.78.100.186/handle/113462/132800]  |
| 专题 | 中国科学院近代物理研究所 |
| 通讯作者 | Li, Qiang |
| 作者单位 | 1.Chinese Acad Sci, Inst Modern Phys, Lanzhou 73000, Gansu, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Key Lab Basic Res Heavy Ion Radiat Applicat Med, Lanzhou 730000, Gansu, Peoples R China 4.Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou 730000, Gansu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shen, Guosheng,Dai, Tianyuan,Li, Qiang,et al. Technical Note: Effect of magnetic fields on the microdosimetry of carbon-ion beams[J]. MEDICAL PHYSICS,2019,46(8):3746-3750. |
| APA | Shen, Guosheng.,Dai, Tianyuan.,Li, Qiang.,Liu, Xinguo.,Dai, Zhongying.,...&Zhang, Xiaofang.(2019).Technical Note: Effect of magnetic fields on the microdosimetry of carbon-ion beams.MEDICAL PHYSICS,46(8),3746-3750. |
| MLA | Shen, Guosheng,et al."Technical Note: Effect of magnetic fields on the microdosimetry of carbon-ion beams".MEDICAL PHYSICS 46.8(2019):3746-3750. |
入库方式： OAI收割
来源：近代物理研究所
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