Online compensation for target motion with scanned particle beams: simulation environment
文献类型：期刊论文
| 作者 | Haberer, T; Li, Q ; Rietzel, E; Kraft, G; Groezinger, SO
|
| 刊名 | PHYSICS IN MEDICINE AND BIOLOGY
 |
| 出版日期 | 2004-07-21 |
| 卷号 | 49期号:8页码:3029-3046 |
| ISSN号 | 0031-9155 |
| DOI | 10.1088/0031-9155/49/14/001 |
| 英文摘要 | Target motion is one of the major limitations of each high precision radiation therapy. Using advanced active beam delivery techniques, such as the magnetic raster scanning system for particle irradiation, the interplay between time-dependent beam and target position heavily distorts the applied dose distribution. This paper presents a simulation environment in which the time-dependent effect of target motion on heavy-ion irradiation can be calculated with dynamically scanned ion beams. In an extension of the existing treatment planning software for ion irradiation of static targets (TRIP) at GSI, the expected dose distribution is calculated as the sum of several sub-distributions for single target motion states. To investigate active compensation for target motion by adapting the position of the therapeutic beam during irradiation, the planned beam positions can be altered during the calculation. Applying realistic parameters to the planned motion-compensation methods at GSI, the effect of target motion on the expected dose uniformity can be simulated for different target configurations and motion conditions. For the dynamic dose calculation, experimentally measured profiles of the beam extraction in time were used. Initial simulations show the feasibility and consistency of an active motion compensation with the magnetic scanning system and reveal some strategies to improve the dose homogeneity inside the moving target. The simulation environment presented here provides an effective means for evaluating the dose distribution for a moving target volume with and without motion compensation. It contributes a substantial basis for the experimental research on the irradiation of moving target volumes with scanned ion beams at GSI which will be presented in upcoming papers. |
| WOS关键词 | 3-DIMENSIONAL DOSE VERIFICATION ; HEAVY-ION THERAPY ; X-RAY-FILMS ; IRRADIATION SYSTEM ; RADIOTHERAPY ; TUMORS |
| WOS研究方向 | Engineering ; Radiology, Nuclear Medicine & Medical Imaging |
| 语种 | 英语 |
| WOS记录号 | WOS:000223285900001 |
| 出版者 | IOP PUBLISHING LTD |
| 公开日期 | 2010-10-29 |
| 源URL | [http://ir.imp.cas.cn/handle/113462/967]  |
| 专题 | 近代物理研究所_近代物理研究所知识存储（2010之前） |
| 通讯作者 | Li, Q |
| 作者单位 | 1.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China 2.Gesell Schwerionenforsch Inst Darmstadt, D-64291 Darmstadt, Germany |
| 推荐引用方式 GB/T 7714 | Haberer, T,Li, Q,Rietzel, E,et al. Online compensation for target motion with scanned particle beams: simulation environment[J]. PHYSICS IN MEDICINE AND BIOLOGY,2004,49(8):3029-3046. |
| APA | Haberer, T,Li, Q,Rietzel, E,Kraft, G,&Groezinger, SO.(2004).Online compensation for target motion with scanned particle beams: simulation environment.PHYSICS IN MEDICINE AND BIOLOGY,49(8),3029-3046. |
| MLA | Haberer, T,et al."Online compensation for target motion with scanned particle beams: simulation environment".PHYSICS IN MEDICINE AND BIOLOGY 49.8(2004):3029-3046. |
入库方式： OAI收割
来源：近代物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。