Measurement of lineal energy spectra at different penetration depths along a radioactive C-9-ion beam
文献类型：期刊论文
| 作者 | Urakabe, E; Matsufuji, N; Li, Q ; Sato, S; Kanazawa, M
|
| 刊名 | HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION
 |
| 出版日期 | 2005-11-01 |
| 卷号 | 29期号:11页码:1041-1046 |
| 关键词 | double irradiation source tissue-equivalent proportional counter lineal energy spectrum dose-averaged lineal energy dose-averaged LET penetration depth |
| ISSN号 | 0254-3052 |
| 英文摘要 | It is expected that a radioactive C-9-ion beam as a type of double irradiation source can increase the curative effect when applying it to heavy-ion cancer therapy, and it has been proved in our previous radiobiological experiment that the relative biological effectiveness (RBE) at the depths around the Bragg peak of a C-9 beam was greater than that of a therapeutic C-12 beam at least by a factor of 2. To characterize the physical basis of a C-9 ion beam applying to radiotherapy, a spherical tissue-equivalent proportional counter (TEPC) was used to measure the lineal energy (y) spectra at different depths along a radioactive C-9-ion beam in this work. Based on the measured spectra, the distribution of dose-averaged lineal energy in depth was derived. Moreover, the measured lineal energy spectra, were converted into the distributions of LET in absorbed dose at the different depths. The distribution of dose-averaged LET in depth, therefore, has been obtained for the C-9 beam. The dose-averaged LETs measured with the TEPC and our preceding parellel-plate proportional counter (PPPC) were compared. It has been found that both the measurements agreed well with each other at the entrance channel of the C-9 beam while the dose-averaged LETs by the TEPC were larger than those by the PPPC around the Bragg peak, i.e. the stopping region of the incident C-9 ions. This coincides with the expectation that all of the delayed alpha particles and protons, which are emitted isotropically during the decays of the C-9 ions, can be included by means of the TEPC measurement. The data sets obtained in this work provide a substantial physical basis for revealing the advantages of C-9 beams in cancer therapy. |
| WOS关键词 | CARBON ION RADIOTHERAPY ; PARTICLE DECAY BEAM ; CANCER-THERAPY ; POTENTIAL APPLICATION ; V79 CELLS ; C-9 ; INACTIVATION ; DEUTERONS ; FACILITY ; PROTONS |
| WOS研究方向 | Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000233323300003 |
| 出版者 | SCIENCE PRESS |
| 公开日期 | 2010-10-29 |
| 源URL | [http://ir.imp.cas.cn/handle/113462/1091]  |
| 专题 | 近代物理研究所_近代物理研究所知识存储（2010之前） |
| 通讯作者 | Li, Q |
| 作者单位 | 1.Natl Inst Radiol Sci, Chiba 2638555, Japan 2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Urakabe, E,Matsufuji, N,Li, Q,et al. Measurement of lineal energy spectra at different penetration depths along a radioactive C-9-ion beam[J]. HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION,2005,29(11):1041-1046. |
| APA | Urakabe, E,Matsufuji, N,Li, Q,Sato, S,&Kanazawa, M.(2005).Measurement of lineal energy spectra at different penetration depths along a radioactive C-9-ion beam.HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION,29(11),1041-1046. |
| MLA | Urakabe, E,et al."Measurement of lineal energy spectra at different penetration depths along a radioactive C-9-ion beam".HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION 29.11(2005):1041-1046. |
入库方式： OAI收割
来源：近代物理研究所
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