Effects of low priming dose of radiation on cell cycle arrest of tumor cells caused by high dose of radiation
文献类型：期刊论文
| 作者 | Gao, QX; Xia, JG; Li, WJ; Wang, JF; Guo, CL; Yang, HS |
| 刊名 | HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION
 |
| 出版日期 | 2005-02-01 |
| 卷号 | 29期号:2页码:201-204 |
| 关键词 | ionizing radiation cell cycle arrest tumor cell DNA damage |
| ISSN号 | 0254-3052 |
| 英文摘要 | Effects of low priming dose of radiation on cell cycle progression in hep G2 and HeLa cells have been investigated. For both,cell lines, cells in the G(2)/M phase are accumulated temporarily after 5cGy gamma-ray exposing, and the proliferation of tumor cells is significantly promoted by low dose radiation. When exposing to 3Gy gamma-ray, only the G(2) phase arrest occurred for hep G(2) cells, and both S and G(2) arrest occurred for HeLa cells. In contrast to treatment with high dose of radiation, when high dose was delivered 4hr after priming dose, pretreatment facilitates the accumulation of hep G2 cells in G(2)/M phase, however, pretreatment does not significantly change the cell cycle progression of HeLa cells. It is concluded that alterations of the cell cycle progression by pretreatment with low dose of radiation are dependent on the type of tumor cell lines. |
| WOS关键词 | ACTIVATED PROTEIN-KINASE ; DNA-DAMAGE RESPONSE ; IONIZING-RADIATION ; RADIOADAPTIVE RESPONSE ; PATHWAY ; REPAIR ; P53 |
| WOS研究方向 | Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000226954500018 |
| 出版者 | SCIENCE CHINA PRESS |
| 公开日期 | 2010-10-29 |
| 源URL | [http://ir.imp.cas.cn/handle/113462/1141]  |
| 专题 | 近代物理研究所_近代物理研究所知识存储（2010之前） |
| 通讯作者 | Xia, JG |
| 作者单位 | 1.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China 2.Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, QX,Xia, JG,Li, WJ,et al. Effects of low priming dose of radiation on cell cycle arrest of tumor cells caused by high dose of radiation[J]. HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION,2005,29(2):201-204. |
| APA | Gao, QX,Xia, JG,Li, WJ,Wang, JF,Guo, CL,&Yang, HS.(2005).Effects of low priming dose of radiation on cell cycle arrest of tumor cells caused by high dose of radiation.HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION,29(2),201-204. |
| MLA | Gao, QX,et al."Effects of low priming dose of radiation on cell cycle arrest of tumor cells caused by high dose of radiation".HIGH ENERGY PHYSICS AND NUCLEAR PHYSICS-CHINESE EDITION 29.2(2005):201-204. |
入库方式： OAI收割
来源：近代物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。