Chromosomal aberrations induced by C-12(6+) ions and Co-60 gamma-rays in mouse immature oocytes
文献类型：期刊论文
| 作者 | Min, FL; Zhang, H ; Duan, X; Yuan, ZG; Xie, Y; Li, WJ; Zhou, GM; Zhou, QM; Bing, L; Li, XD
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| 刊名 | MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
 |
| 出版日期 | 2006-03-20 |
| 卷号 | 595期号:1--2页码:37-41 |
| 关键词 | C-12(6+) heavy ion chromosomal aberration oocytes mouse |
| ISSN号 | 0027-5107 |
| DOI | 10.1016/j.mrfmmm.2005.10.010 |
| 英文摘要 | The ovaries of Kun-Ming strain mice (3 weeks) were irradiated with different doses of C-12(6+) ion or Co-60 gamma-ray. Chromosomal aberrations were analyzed in metaphase II oocytes at 7 weeks after irradiation. The relative biological effectiveness (RBE) of C C-12(6+) ion was calculated with respect to Co-60 gamma-ray for the induction of chromosornal aberrations. The C-12(6+) ion and Co-60 gamma-ray dose-response relationships for chromosomal aberrations were plotted by linear quadratic models. The data showed that there was a dose-related increase in frequency of chromosomal aberrations in all the treated groups compared to controls. The RBE values for C-12(6+) ions relative to (CO)-C-60 gamma-rays were 2.49, 2.29, 1.57, 1.42 or 1.32 for the doses of 0.5, 1.0, 2.07 4.0 or 6.0 Gy, respectively. Moreover, a different distribution of the various types of aberrations has been found for C-12(6+) ion and Co-60 gamma-ray irradiations. The dose-response relationships for C-12(6+) ion and (CO)-C-60 gamma-ray exhibited positive correlations. The results from the present study may be helpful for assessing genetic damage following exposure of immature oocytes to ionizing radiation. (c) 2005 Elsevier B.V. All rights reserved. |
| WOS关键词 | FEMALE GERM-CELLS ; X-RAYS ; RADIATION ; IRRADIATION ; ANOMALIES ; MICE ; RADIOSENSITIVITY ; DAMAGE ; OVARY |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Genetics & Heredity ; Toxicology |
| 语种 | 英语 |
| WOS记录号 | WOS:000236049300006 |
| 出版者 | ELSEVIER SCIENCE BV |
| 公开日期 | 2010-10-29 |
| 源URL | [http://ir.imp.cas.cn/handle/113462/5517]  |
| 专题 | 近代物理研究所_近代物理研究所知识存储（2010之前） 近代物理研究所_生物物理研究室 |
| 通讯作者 | Zhang, H |
| 作者单位 | Chinese Acad Sci, Inst Modern Phys, Dept Med Phys, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Min, FL,Zhang, H,Duan, X,et al. Chromosomal aberrations induced by C-12(6+) ions and Co-60 gamma-rays in mouse immature oocytes[J]. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS,2006,595(1--2):37-41. |
| APA | Min, FL.,Zhang, H.,Duan, X.,Yuan, ZG.,Xie, Y.,...&Li, XD.(2006).Chromosomal aberrations induced by C-12(6+) ions and Co-60 gamma-rays in mouse immature oocytes.MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS,595(1--2),37-41. |
| MLA | Min, FL,et al."Chromosomal aberrations induced by C-12(6+) ions and Co-60 gamma-rays in mouse immature oocytes".MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 595.1--2(2006):37-41. |
入库方式： OAI收割
来源：近代物理研究所
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