A method on theoretical simulation of chromosome breaks in cells exposed to heavy ions
文献类型：期刊论文
| 作者 | Yang, Jianshe1,2,3; Li, Wenjian2 ; Jing, Xigang2; Wang, Zhuanzi2; Gao, Qingxiang2
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| 刊名 | RADIOLOGY AND ONCOLOGY
 |
| 出版日期 | 2008 |
| 卷号 | 42期号:1页码:32-38 |
| 关键词 | theoretical simulation chromosome breaks cells heavy ions |
| ISSN号 | 1318-2099 |
| DOI | 10.2478/v10019-007-0036-3 |
| 英文摘要 | Background. The aim of this study is to assess an easy and quick method on simulating chromosome breaks in cells exposed to heavy charged particles. Methods. The theoretical value of chromosome break was calculated, and the validated comparison with the experimental value by using a premature chromosome condensation technique was done. Results. A good consistence was found to be appeared between the theoretical and experimental value. Conclusions. This suggested that a higher relative biological effectiveness of heavy ions was closely correlated with its physical characteristics and besides, a safe approach on predicting chromosome breaks in cells exposed to heavy ions at off-line environment come to be considered. Furthermore, three key factors influencing the theoretical simulation was investigated and discussed. |
| WOS关键词 | INTRINSIC RADIOSENSITIVITY ; HUMAN FIBROBLASTS ; CONDENSATION ; CARCINOMA ; RADIATION ; SURVIVAL ; ABERRATIONS ; INDUCTION ; CERVIX ; DAMAGE |
| WOS研究方向 | Oncology ; Radiology, Nuclear Medicine & Medical Imaging |
| 语种 | 英语 |
| WOS记录号 | WOS:000257813000005 |
| 出版者 | ASSOC RADIOLOGY & ONCOLOGY |
| 公开日期 | 2010-10-29 |
| 源URL | [http://ir.imp.cas.cn/handle/113462/5681]  |
| 专题 | 近代物理研究所_近代物理研究所知识存储（2010之前） 近代物理研究所_生物物理研究室 |
| 通讯作者 | Yang, Jianshe |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Appl Phys, Shanghai, Peoples R China 2.Chinese Acad Sci, Inst Modern Phys, Lanzhou, Peoples R China 3.NW Normal Univ, Sch Life Sci, Lanzhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Jianshe,Li, Wenjian,Jing, Xigang,et al. A method on theoretical simulation of chromosome breaks in cells exposed to heavy ions[J]. RADIOLOGY AND ONCOLOGY,2008,42(1):32-38. |
| APA | Yang, Jianshe,Li, Wenjian,Jing, Xigang,Wang, Zhuanzi,&Gao, Qingxiang.(2008).A method on theoretical simulation of chromosome breaks in cells exposed to heavy ions.RADIOLOGY AND ONCOLOGY,42(1),32-38. |
| MLA | Yang, Jianshe,et al."A method on theoretical simulation of chromosome breaks in cells exposed to heavy ions".RADIOLOGY AND ONCOLOGY 42.1(2008):32-38. |
入库方式： OAI收割
来源：近代物理研究所
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