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Studies on advantages of heavy ions in radiotherapy compared with gamma-rays

文献类型：期刊论文

作者Guo Chuanling; Wang Jufang; Jin Xiaodong; Jing Xigang; Li Renmin; Wei Wei; Li Wenjian
刊名NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS
出版日期2007-06-01
卷号259期号:2页码:997-1003
关键词heavy ions radiotherapy survival fraction RBE
ISSN号0168-583X
DOI10.1016/j.nimb.2007.03.010
英文摘要Hepatoma and melanoma cells were exposed to C-12(6+) beams generated by HIRFL facility and gamma-rays and the cell response was studied by colony assays as well as the analysis of RBE of carbon ions was evolved. The survival curves of cells irradiated by heavy ions were different from those of cells irradiated by gamma-rays. And two kinds of cell showed the obvious discrepancy in response to the photon and ion irradiation. The results showed that heavy ions have special physical properties and mighty potency to kill cell in both single and fractional irradiation meanwhile it can kill tumor cells with high radioresistance more efficiently. When involved in clinical therapy, heavy ions will enhance the therapy efficiency and decrease the suffering of patients because it can impair the repair for sublethal damage of cells which can lead to fewer irradiation fractions. (c) 2007 Elsevier B.V. All rights reserved.
WOS关键词BREAKS
WOS研究方向Instruments & Instrumentation ; Nuclear Science & Technology ; Physics
语种英语
WOS记录号WOS:000247322500025
出版者ELSEVIER SCIENCE BV
公开日期2010-10-29
源URL[http://ir.imp.cas.cn/handle/113462/5957]  
专题近代物理研究所_近代物理研究所知识存储（2010之前）
通讯作者Guo Chuanling
作者单位1.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714		 Guo Chuanling,Wang Jufang,Jin Xiaodong,et al. Studies on advantages of heavy ions in radiotherapy compared with gamma-rays[J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,2007,259(2):997-1003.
APA Guo Chuanling.,Wang Jufang.,Jin Xiaodong.,Jing Xigang.,Li Renmin.,...&Li Wenjian.(2007).Studies on advantages of heavy ions in radiotherapy compared with gamma-rays.NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,259(2),997-1003.
MLA Guo Chuanling,et al."Studies on advantages of heavy ions in radiotherapy compared with gamma-rays".NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS 259.2(2007):997-1003.

入库方式： OAI收割

来源：近代物理研究所

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