Therapeutic techniques applied in the heavy-ion therapy at IMP
文献类型：期刊论文
| 作者 | Sihver, Lembit2,3,5; Li, Qiang1,4
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| 刊名 | NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS
 |
| 出版日期 | 2011-04-01 |
| 卷号 | 269页码:664-670 |
| 关键词 | Heavy-ion therapy Therapy terminal Beam delivery Treatment planning Patient treatment |
| ISSN号 | 0168-583X |
| DOI | 10.1016/j.nimb.2011.01.125 |
| 英文摘要 | Superficially-placed tumors have been treated with carbon ions at the Institute of Modern Physics (IMP), Chinese Academy of Sciences (CAS), since November 2006. Up to now, 103 patients have been irradiated in the therapy terminal of the heavy ion research facility in Lanzhou (HIRFL) at IMP, where carbon-ion beams with energies up to 100 MeV/u can be supplied and a passive beam delivery system has been developed and commissioned. A number of therapeutic and clinical experiences concerning heavy-ion therapy have been acquired at IMP. To extend the heavy-ion therapy project to deep-seated tumor treatment, a horizontal beam line dedicated to this has been constructed in the cooling storage ring (CSR), which is a synchrotron connected to the HIRFL as an injector, and is now in operation. Therapeutic high-energy carbon-ion beams, extracted from the HIRFL-CSR through slow extraction techniques, have been supplied in the deep-seated tumor therapy terminal. After the beam delivery, shaping and monitoring devices installed in the therapy terminal at HIRFL-CSR were validated through therapeutic beam tests, deep-seated tumor treatment with high-energy carbon ions started in March 2009. The therapeutic techniques in terms of beam delivery system, conformal irradiation method and treatment planning used at IMP are introduced in this paper. (C) 2011 Elsevier B.V. All rights reserved. |
| WOS关键词 | BEAM 3-DIMENSIONAL IRRADIATION ; MICRODOSIMETRIC-KINETIC-MODEL ; LOCAL EFFECT MODEL ; CELL-SURVIVAL ; CONFORMAL IRRADIATION ; PARTICLE THERAPY ; LIQUID WATER ; RADIOTHERAPY ; RADIATION ; SYSTEM |
| 资助项目 | National Basic Research Program of China (973 Program)[2010CB834203] ; National Natural Science Foundation of China[10835011] ; National Natural Science Foundation of China[10905080] ; National Natural Science Foundation of China[11075191] ; Science and Technology Development Project of Lanzhou City[2008-sr-10] ; Science and Technology Development Project of Lanzhou City[2009-2-12] ; K.C.Wong Education Foundation, Hong Kong |
| WOS研究方向 | Instruments & Instrumentation ; Nuclear Science & Technology ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000289183000007 |
| 出版者 | ELSEVIER SCIENCE BV |
| 资助机构 | National Basic Research Program of China (973 Program) ; National Natural Science Foundation of China ; Science and Technology Development Project of Lanzhou City ; K.C.Wong Education Foundation, Hong Kong |
| 源URL | [http://ir.impcas.ac.cn/handle/113462/18590]  |
| 专题 | 近代物理研究所_医学物理研究室 近代物理研究所_生物物理研究室 |
| 通讯作者 | Li, Qiang |
| 作者单位 | 1.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Gansu, Peoples R China 2.Roanoke Coll, Salem, VA 24153 USA 3.Chalmers, SE-41296 Gothenburg, Sweden 4.Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou 730000, Gansu, Peoples R China 5.Texas A&M Univ, College Stn, TX 77843 USA |
| 推荐引用方式 GB/T 7714 | Sihver, Lembit,Li, Qiang. Therapeutic techniques applied in the heavy-ion therapy at IMP[J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,2011,269:664-670. |
| APA | Sihver, Lembit,&Li, Qiang.(2011).Therapeutic techniques applied in the heavy-ion therapy at IMP.NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,269,664-670. |
| MLA | Sihver, Lembit,et al."Therapeutic techniques applied in the heavy-ion therapy at IMP".NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS 269(2011):664-670. |
入库方式： OAI收割
来源：近代物理研究所
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