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Ionizing radiation induced biological effects in three-dimensional cell cultures

文献类型：期刊论文

作者Xue, Gang1,2; Pan, Dong1,2; Hu, Burong2; Zhu, Jiayun1,2
刊名RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI
出版日期2014-03-01
卷号25页码:S81-S86
关键词Three-dimensional Cell Culture (Tdcc) Biological Effects Ionizing Radiation Potential Mechanism
ISSN号2037-4631
DOI10.1007/s12210-013-0260-2
文献子类Article
英文摘要In vitro three-dimensional cell culture (TDCC) is a new cell culture model that owns its unique perspectives by mimicking features of the in vivo environment and is believed to have the potential to bridge the gap between traditional cell culture and animal models in biological and medicinal studies. Despite the generally harmful and potentially lethal effects, ionizing radiation also demonstrates health benefits in radiotherapy for cancers. This review mainly introduced the three-dimensional cell culture model and different biological effects induced by ionizing radiation, as well as their potential mechanism(s) as compared to traditional monolayer cultures.
WOS关键词GENE-EXPRESSION ; DNA METHYLTRANSFERASES ; EXTRACELLULAR-MATRIX ; TISSUE ARCHITECTURE ; IN-VITRO ; HUMAN FIBROBLASTS ; ALPHA-PARTICLES ; CANCER ; 3D ; SCAFFOLDS
资助项目National Natural Science Foundation of China[31170803]
WOS研究方向Science & Technology - Other Topics
语种英语
WOS记录号WOS:000332688700016
出版者SPRINGER-VERLAG ITALIA SRL
源URL[http://119.78.100.186/handle/113462/49613]  
专题近代物理研究所_空间辐射生物研究室
通讯作者Hu, Burong
作者单位1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
2.Chinese Acad Sci, Inst Modern Phys, Dept Space Radiobiol, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714		 Xue, Gang,Pan, Dong,Hu, Burong,et al. Ionizing radiation induced biological effects in three-dimensional cell cultures[J]. RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI,2014,25:S81-S86.
APA Xue, Gang,Pan, Dong,Hu, Burong,&Zhu, Jiayun.(2014).Ionizing radiation induced biological effects in three-dimensional cell cultures.RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI,25,S81-S86.
MLA Xue, Gang,et al."Ionizing radiation induced biological effects in three-dimensional cell cultures".RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI 25(2014):S81-S86.

入库方式： OAI收割

来源：近代物理研究所

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