Avoid online radiation risk: Theoretical simulation of chromosome breaks in cells exposed to heavy ions
文献类型：期刊论文
| 作者 | Zhou, Gang2; Wang, Qiang2; Yang, Hanshe1,2; Li, Wenjian1 ; Jing, Xigang1
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| 刊名 | ADVANCES IN SPACE RESEARCH
 |
| 出版日期 | 2011-06-01 |
| 卷号 | 47页码:2039-2043 |
| ISSN号 | 0273-1177 |
| 关键词 | Theoretical simulation Chromosome break Cell Heavy ions |
| DOI | 10.1016/j.asr.2011.01.027 |
| 英文摘要 | In this study, we report an easy and quick method on simulating chromosome breaks in cells exposed to heavy charged particles. The theoretical value of chromosome break was calculated, and validated comparison with experimental value by using premature chromosome condensation technique. A good consistency was found between theoretical and experimental value. This suggested that higher relative biological effectiveness of heavy ions was closely correlated with its physical characteristics. Also, a safe approach on predicting chromosome breaks in cells exposed to heavy ions at off-line environment can be considered. Furthermore, three key factors influencing the theoretical simulation was investigated and discussed. Crown copyright (C) 2011 Published by Elsevier Ltd. on behalf of COSPAR. All rights reserved. |
| WOS关键词 | INTRINSIC RADIOSENSITIVITY ; CHARGED-PARTICLES ; HUMAN FIBROBLASTS ; LINES ; PCC ; CONDENSATION ; INDUCTION ; CARCINOMA ; SURVIVAL ; ABERRATIONS |
| 资助项目 | National Natural Science Foundation Committee[10335050] ; Sciences and Technology Ministry of People's Republic of China[2003CCB00200] ; Northwest Normal University[NWNU-KJCXGC-03-57] ; Northwest Normal University[NWNU-KJCXGC-03-49] |
| WOS研究方向 | Astronomy & Astrophysics ; Geology ; Meteorology & Atmospheric Sciences |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCI LTD |
| WOS记录号 | WOS:000291296100020 |
| 资助机构 | National Natural Science Foundation Committee ; Sciences and Technology Ministry of People's Republic of China ; Northwest Normal University |
| 源URL | [http://119.78.100.186/handle/113462/34079]  |
| 专题 | 近代物理研究所_生物物理研究室 |
| 通讯作者 | Yang, Hanshe |
| 作者单位 | 1.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Gansu, Peoples R China 2.NW Normal Univ, Sch Life Sci, Lanzhou 730070, Gansu, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Gang,Wang, Qiang,Yang, Hanshe,et al. Avoid online radiation risk: Theoretical simulation of chromosome breaks in cells exposed to heavy ions[J]. ADVANCES IN SPACE RESEARCH,2011,47:2039-2043. |
| APA | Zhou, Gang,Wang, Qiang,Yang, Hanshe,Li, Wenjian,&Jing, Xigang.(2011).Avoid online radiation risk: Theoretical simulation of chromosome breaks in cells exposed to heavy ions.ADVANCES IN SPACE RESEARCH,47,2039-2043. |
| MLA | Zhou, Gang,et al."Avoid online radiation risk: Theoretical simulation of chromosome breaks in cells exposed to heavy ions".ADVANCES IN SPACE RESEARCH 47(2011):2039-2043. |
入库方式： OAI收割
来源：近代物理研究所
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