Simulated microgravity increases heavy ion radiation-induced apoptosis in human B lymphoblasts
文献类型:期刊论文
作者 | Meng, Yue2; Yan, Siqi3,4; Wang, Zhuanzi3![]() ![]() ![]() |
刊名 | LIFE SCIENCES
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出版日期 | 2014-03-03 |
卷号 | 97页码:123-128 |
关键词 | Heavy Ion radiatIon Simulated Microgravity Apoptosis Reactive Oxygen Species Hmy2.cir Cells |
ISSN号 | 0024-3205 |
DOI | 10.1016/j.lfs.2013.12.008 |
文献子类 | Article |
英文摘要 | Aims: Microgravity and radiation, common in space, are the main factors influencing astronauts' health in space flight, but their combined effects on immune cells are extremely limited. Therefore, the effect of simulated microgravity on heavy ion radiation-induced apoptosis, and reactive oxygen species (ROS)-sensitive apoptosis signaling were investigated in human B lymphoblast HMy2.CIR cells. |
WOS关键词 | IONIZING-RADIATION ; H2O2-INDUCED APOPTOSIS ; HUMAN-LYMPHOCYTES ; OXIDATIVE STRESS ; CELLS ; KINASE ; ACTIVATION ; EXPOSURE ; PATHWAY ; OXYGEN |
资助项目 | National Natural Science Foundation of China[11179002] ; National Natural Science Foundation of China[31071917] ; National Natural Science Foundation of China[31171121] |
WOS研究方向 | Research & Experimental Medicine ; Pharmacology & Pharmacy |
语种 | 英语 |
WOS记录号 | WOS:000331920800005 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
源URL | [http://119.78.100.186/handle/113462/49277] ![]() |
专题 | 近代物理研究所_生物物理研究室 |
通讯作者 | Lin, Changjun |
作者单位 | 1.Fudan Univ, Inst Radiol Med, Shanghai 200032, Peoples R China 2.Lanzhou Univ, Sch Life Sci, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China 4.Lanzhou Univ, Sch Nucl Sci & Technol, Lanzhou 730000, Peoples R China |
推荐引用方式 GB/T 7714 | Meng, Yue,Yan, Siqi,Wang, Zhuanzi,et al. Simulated microgravity increases heavy ion radiation-induced apoptosis in human B lymphoblasts[J]. LIFE SCIENCES,2014,97:123-128. |
APA | Meng, Yue.,Yan, Siqi.,Wang, Zhuanzi.,Wei, Wei.,Lin, Changjun.,...&Mi, Xiangquan.(2014).Simulated microgravity increases heavy ion radiation-induced apoptosis in human B lymphoblasts.LIFE SCIENCES,97,123-128. |
MLA | Meng, Yue,et al."Simulated microgravity increases heavy ion radiation-induced apoptosis in human B lymphoblasts".LIFE SCIENCES 97(2014):123-128. |
入库方式: OAI收割
来源:近代物理研究所
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