Cancer risk of high-charge and -energy ions and the biological effects of the induced secondary particles in space
文献类型：期刊论文
| 作者 | Ding, Nan1,2,3 ; Zhou, Guangming1; Wang, Tieshan3; Wang, Jufang1; Li, He1; He, Jinpeng1,2; Hu, Wentao1; Pei, Hailong1,2
|
| 刊名 | RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI
 |
| 出版日期 | 2014-03-01 |
| 卷号 | 25页码:S59-S63 |
| 关键词 | Space Radiation Tumorigenesis Secondary Particles Hze |
| ISSN号 | 2037-4631 |
| DOI | 10.1007/s12210-014-0288-y |
| 文献子类 | Article |
| 英文摘要 | Space exploration represents great challenge to astronauts' health because of the uncertain risk of carcinogenesis caused by space radiation, in which high-charge and -energy (HZE) particles should be the most harmful components. Although there are a number of researches confirming that HZE particles have more severe biological effects including tumorigenesis than low-LET radiations, it is still very hard to accurately estimate the cancer risk of space HZE radiation due to the lack of suitable epidemiological data on exposures to low-dose HZE particle irradiation. Ground-based experiments on high-energy heavy ion accelerators might be appropriate complement for understanding the risk of space radiation. On the other hand, effective countermeasures to reduce the radiation damage are essential to manned space exploration. Up to now, shielding is still the most practical way to attenuate biological responses of space radiation. However, the knowledge on the biological effects of secondary particles produced by the interaction of HZE particles with shielding materials is required for space shielding design. This review will discuss the issues of space HZE particles and the biological effects of secondary particles produced by the interaction of space radiation and shielding materials. |
| WOS关键词 | RADIATION PROTECTION ; DNA-DAMAGE ; DEEP SPACE ; ASTRONAUTS ; CELLS ; FIBROBLASTS ; LYMPHOCYTES ; EXPLORATION ; ABERRATIONS ; INDUCTION |
| 资助项目 | National Natural Science Foundation of China[31070763] ; National Natural Science Foundation of China[U1232125] ; National Natural Science Foundation of China[31270895] |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000332688700012 |
| 出版者 | SPRINGER-VERLAG ITALIA SRL |
| 源URL | [http://119.78.100.186/handle/113462/49497]  |
| 专题 | 近代物理研究所_生物物理研究室 |
| 通讯作者 | Zhou, Guangming |
| 作者单位 | 1.Chinese Acad Sci, Inst Modern Phys, Dept Space Radiobiol, Lanzhou 730000, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Lanzhou Univ, Sch Nucl Sci & Technol, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, Nan,Zhou, Guangming,Wang, Tieshan,et al. Cancer risk of high-charge and -energy ions and the biological effects of the induced secondary particles in space[J]. RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI,2014,25:S59-S63. |
| APA | Ding, Nan.,Zhou, Guangming.,Wang, Tieshan.,Wang, Jufang.,Li, He.,...&Pei, Hailong.(2014).Cancer risk of high-charge and -energy ions and the biological effects of the induced secondary particles in space.RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI,25,S59-S63. |
| MLA | Ding, Nan,et al."Cancer risk of high-charge and -energy ions and the biological effects of the induced secondary particles in space".RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI 25(2014):S59-S63. |
入库方式： OAI收割
来源：近代物理研究所
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