Mutagenesis, Screening and industrialization of High Avermectin B1a Producing Strains from Streptomyces Avermitilis irradiated by C-12(6+) ion beam
文献类型：会议论文
| 作者 | Zhang, XD; Ai, ZJ; Liu, Jing; Ma, Xiaoqi2; Bo, Yongheng1; Yarlagadda, P; Wang, Shuyang1,2 ; Chen, Jihong2; Li, Wenjiang2; Liang, Jianping2
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| 出版日期 | 2011 |
| 关键词 | Irradiation Ion Beam of C-12(6+) streptomyces avermitilis Screening industrialization |
| 卷号 | 339 |
| DOI | 10.4028/www.scientific.net/AMR.339.652 |
| 页码 | 652-+ |
| 英文摘要 | Heavy ion irradiation induced mutation is a unique method of physical mutation, with various parameters, high LET and RBE characteristic. The spore suspension of streptomyces avermitilis were irradiated by carbon ions with doses of 0, 30, 40, 50, 60 and 70 Gy. The high avermectin producing strain was successfully obtained after the mutagenesis processing by heavy ion beam and the screening of orthomutation strains. Two strains(No.203 and No.148) which potency was 52004 mu g/ml was sieved and its potency increased 38.64% than the original strain. The obtained strains were used for 1 ton fermentation tank and the pilot 5-ton fermentation tank amplification tests. |
| 会议录 | ADVANCED MANUFACTURING SYSTEMS
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| 会议录出版者 | TRANS TECH PUBLICATIONS LTD |
| 会议录出版地 | KREUZSTRASSE 10, 8635 DURNTEN-ZURICH, SWITZERLAND |
| 语种 | 英语 |
| 资助项目 | Science and technology projects in Lanzhou[2009-2-13] |
| WOS研究方向 | Engineering ; Materials Science |
| WOS记录号 | WOS:000309383100126 |
| 源URL | [http://119.78.100.186/handle/113462/58501]  |
| 专题 | 近代物理研究所_生物物理研究室 |
| 通讯作者 | Wang, Shuyang |
| 作者单位 | 1.Gansu Agr Univ, Lanzhou 730070, Peoples R China 2.Chinese Acad Sci, Inst Modern Phys, Dept Biol Phys, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, XD,Ai, ZJ,Liu, Jing,et al. Mutagenesis, Screening and industrialization of High Avermectin B1a Producing Strains from Streptomyces Avermitilis irradiated by C-12(6+) ion beam[C]. 见:. |
入库方式： OAI收割
来源：近代物理研究所
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