Mini-SOBPs Based Combinatorial Irradiation Method in Heavy Ion Radiotherapy
文献类型：期刊论文
| 作者 | Ji Tengfei; Liu Xinguo ; Dai Zhongying; He Pengbo; Yan Yuanlin; Huang Qiyan; Li Qiang
|
| 刊名 | Nuclear Physics Review
 |
| 出版日期 | 2016 |
| 卷号 | 33页码:345-352 |
| ISSN号 | 1007-4627 |
| 英文摘要 | In layer-stacking conformal heavy-ion therapy based on passive beam delivery system, it is necessary to minimize the layer numbers and reduce irradiation time for layer-stacking conformal heavy-ion therapy. Gaussian shaped mini spread-out Bragg peaks (mini-SOBP) were generated by mini ridge filters (mini-RF) for monoenergetic heavy ion beams. It is effective to minimize the layer number by using mini-SOBPs with the bigger full width at the half maximum (FWHM), but in this way the distal dose fall-off distance of a spread-out Bragg peak (SOBP) will be enlarged, increasing the radiation damage to normal tissue or organ at risk behind the target volume. This issue could be solved by using mini-SOBPs based combinatorial irradiation method. In this study, Gaussian shaped mini-SOBPs with two different FWHMs were generated by two different mini-RFs for monoenergetic heavy ion beams. Based on radiobiological model calculations and dose optimizations, the mini-SOBPs based combinatorial irradiation method was confirmed to reduce the distal dose fall-off distances of SOBPs while minimizing the layer numbers for layer-stacking conformal heavy-ion therapy. |
| CSCD记录号 | CSCD:5871406 |
| 源URL | [http://119.78.100.186/handle/113462/59891]  |
| 专题 | 近代物理研究所_兰州重离子研究装置 近代物理研究所_生物物理研究室 |
| 推荐引用方式 GB/T 7714 | Ji Tengfei,Liu Xinguo,Dai Zhongying,et al. Mini-SOBPs Based Combinatorial Irradiation Method in Heavy Ion Radiotherapy[J]. Nuclear Physics Review,2016,33:345-352. |
| APA | Ji Tengfei.,Liu Xinguo.,Dai Zhongying.,He Pengbo.,Yan Yuanlin.,...&Li Qiang.(2016).Mini-SOBPs Based Combinatorial Irradiation Method in Heavy Ion Radiotherapy.Nuclear Physics Review,33,345-352. |
| MLA | Ji Tengfei,et al."Mini-SOBPs Based Combinatorial Irradiation Method in Heavy Ion Radiotherapy".Nuclear Physics Review 33(2016):345-352. |
入库方式： OAI收割
来源：近代物理研究所
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