Damage of Plasmid DNA Induced by Carbon Ion Beam
文献类型：期刊论文
| 作者 | Li Wenjian ; Gao Qingxiang; Wei Zengquan; Ma Qiufeng; Li Qiang; Feng Yan; Zhou Guangming
|
| 刊名 | Acta laser biology sinica
 |
| 出版日期 | 2003 |
| 卷号 | 12页码:337-340 |
| ISSN号 | 1007-7146 |
| 英文摘要 | To verify our hypothesis of the correlation between DNA sequence and the non-random distribution of DNA double-strand break (DSB), pUC18 was irradiated by 32keV/mum ~(12)C~(5+) ions or 45keV/mum ~(13)C~(6+) ions. Agarose gel electrophoresis and restriction endonuclease were employed to analysis the DNA beaks and their distribution. Dose response and the distribution of DNA fragments were obtained. Besides the linear DNA band induced by one DSB, another linear DNA band was found. After treatment with restriction endonuclease, a new linear DNA band emerged. It is testified that the distribution of DSB fragments is non-random. This implies that there may be relatively sensitive sites to ionizing radiation in DNA molecules. |
| CSCD记录号 | CSCD:1174164 |
| 源URL | [http://119.78.100.186/handle/113462/59913]  |
| 专题 | 近代物理研究所_兰州重离子研究装置 近代物理研究所_生物物理研究室 |
| 推荐引用方式 GB/T 7714 | Li Wenjian,Gao Qingxiang,Wei Zengquan,et al. Damage of Plasmid DNA Induced by Carbon Ion Beam[J]. Acta laser biology sinica,2003,12:337-340. |
| APA | Li Wenjian.,Gao Qingxiang.,Wei Zengquan.,Ma Qiufeng.,Li Qiang.,...&Zhou Guangming.(2003).Damage of Plasmid DNA Induced by Carbon Ion Beam.Acta laser biology sinica,12,337-340. |
| MLA | Li Wenjian,et al."Damage of Plasmid DNA Induced by Carbon Ion Beam".Acta laser biology sinica 12(2003):337-340. |
入库方式： OAI收割
来源：近代物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。