Irradiated survival effect of melanoma B16 cells at different penetration depths of intermediate energy heavy-ion beams
文献类型：期刊论文
| 作者 | Li Qiang ; Zhou Guangming; Wang Jufang; Li Wenjian; Wen Xiaoqiong; Dang Bingrong; Xie Hongmei; Wei Zengquan
|
| 刊名 | Nuclear Techniques
 |
| 出版日期 | 2001 |
| 卷号 | 24页码:277-82 |
| ISSN号 | 0253-3219 |
| 英文摘要 | Survival fractions of melanoma B16 cells at different penetration depths exposed to 49.30 MeV/u 12C ion beam and modulated 74.55 MeV/u 12C ion beam with a ridge filter to form a spread-out Bragg peak (SOBP) were measured. The results show the survival response of B16 cells as the biological endpoint to heavy ions increases synchronously with the deposited energy along the beam traversal, that is, the survival fraction near or at the Bragg peak or SOBP is far lower than that at the beam's entrance or exit channel. Comparisons of the experimental data with calculated survival fractions at different depths predicted by the linear-quadratic survival model combined with dose-averaged LET display a good agreement within the experimental errors. It is suggested that the linear quadratic model combined with dose-averaged LET possibly is a valid way to calculate the survival effect of B16 cells along the beam penetration under the exposure of the intermediate energy heavy ion beam. |
| WOS记录号 | INSPEC:6992715 |
| 源URL | [http://119.78.100.186/handle/113462/59918]  |
| 专题 | 近代物理研究所_兰州重离子研究装置 近代物理研究所_生物物理研究室 |
| 推荐引用方式 GB/T 7714 | Li Qiang,Zhou Guangming,Wang Jufang,et al. Irradiated survival effect of melanoma B16 cells at different penetration depths of intermediate energy heavy-ion beams[J]. Nuclear Techniques,2001,24:277-82. |
| APA | Li Qiang.,Zhou Guangming.,Wang Jufang.,Li Wenjian.,Wen Xiaoqiong.,...&Wei Zengquan.(2001).Irradiated survival effect of melanoma B16 cells at different penetration depths of intermediate energy heavy-ion beams.Nuclear Techniques,24,277-82. |
| MLA | Li Qiang,et al."Irradiated survival effect of melanoma B16 cells at different penetration depths of intermediate energy heavy-ion beams".Nuclear Techniques 24(2001):277-82. |
入库方式： OAI收割
来源：近代物理研究所
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