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Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine
文献类型：期刊论文
| 作者 | Niu, Xiu-Nan5,6; Chi, Hao5,6; Liu, Chao5,6; Yang, Hao5,6; Zeng, Wen-Feng5,6; Wu, Long5,6; Zhou, Wen-Jing5,6; Wang, Rui-Min5,6; Ding, Yue-He4; Zhang, Yao1,2,3 |
| 刊名 | NATURE BIOTECHNOLOGY
 |
| 出版日期 | 2018-11-01 |
| 卷号 | 36期号:11页码:1059-+ |
| ISSN号 | 1087-0156 |
| DOI | 10.1038/nbt.4236 |
| 英文摘要 | We present a sequence-tag-based search engine, Open-pFind, to identify peptides in an ultra-large search space that includes coeluting peptides, unexpected modifications and digestions. Our method detects peptides with higher precision and speed than seven other search engines. Open-pFind identified 70-85% of the tandem mass spectra in four large-scale datasets and 14,064 proteins, each supported by at least two protein-unique peptides, in a human proteome dataset. |
| 资助项目 | National Key Research and Development Program of China[2016YFA0501300] ; National Key Research and Development Program of China[2017YFA0505100] ; National Key Research and Development Program of China[2017YFC0906600] ; National Key Research and Development Program of China[2012CB316502] ; Youth Innovation Promotion Association CAS[2014091] ; National Natural Science Foundation of China[31470805] ; National Natural Science Foundation of China[31670834] ; National Natural Science Foundation of China[31700727] ; National Natural Science Foundation of China[21475141] ; CAS Interdisciplinary Innovation Team[Y604061000] ; International Collaboration Program[2014DFB30020] ; Beijing Training Project for The Leading Talents in ST[Z161100004916024] |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000450374000018 |
| 出版者 | NATURE PUBLISHING GROUP |
| 源URL | [http://119.78.100.204/handle/2XEOYT63/4335]  |
| 专题 | 中国科学院计算技术研究所期刊论文_英文 |
| 通讯作者 | Chi, Hao; He, Si-Min |
| 作者单位 | 1.Sun Yat Sen Univ, Coll Ecol & Evolut, Guangdong Prov Key Lab Plant Resources, Guangzhou, Guangdong, Peoples R China 2.Sun Yat Sen Univ, Coll Ecol & Evolut, State Key Lab Biocontrol, Guangzhou, Guangdong, Peoples R China 3.Beijing Inst Life, Natl Ctr Prot Sci Beijing, Beijing Proteome Res Ctr, State Key Lab Prote, Beijing, Peoples R China 4.Natl Inst Biol Sci, Beijing, Peoples R China 5.Univ Chinese Acad Sci, Beijing, Peoples R China 6.Chinese Acad Sci, Key Lab Intelligent Informat Proc, Inst Comp Technol, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Niu, Xiu-Nan,Chi, Hao,Liu, Chao,et al. Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine[J]. NATURE BIOTECHNOLOGY,2018,36(11):1059-+. |
| APA | Niu, Xiu-Nan.,Chi, Hao.,Liu, Chao.,Yang, Hao.,Zeng, Wen-Feng.,...&He, Si-Min.(2018).Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine.NATURE BIOTECHNOLOGY,36(11),1059-+. |
| MLA | Niu, Xiu-Nan,et al."Comprehensive identification of peptides in tandem mass spectra using an efficient open search engine".NATURE BIOTECHNOLOGY 36.11(2018):1059-+. |
入库方式： OAI收割
来源：计算技术研究所
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