Bioconcentration, depuration and toxicity of Pb in the presence of titanium dioxide nanoparticles in zebrafish larvae
文献类型:期刊论文
作者 | Hu, Shengchao1,2; Han, Jian2; Yang, Lihua2; Li, Sen1,3; Guo, Yongyong2; Zhou, Bingsheng2; Wu, Hongjuan1 |
刊名 | AQUATIC TOXICOLOGY
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出版日期 | 2019-09-01 |
卷号 | 214期号:1页码:10 |
关键词 | Lead Titanium dioxide nanoparticles Bioconcentration Deputation Toxicity Zebrafish larvae |
ISSN号 | 0166-445X |
DOI | 10.1016/j.aquatox.2019.105257 |
英文摘要 | The interactions between nanoparticles (NPs) and metals in aquatic environments may modify the bioavailability and toxicity of metals to organisms. In this study, we investigated the effects of titanium dioxide NPs (n-TiO2) on the bioconcentration, depuration, and neurotoxic effects of lead (Pb) in zebrafish larvae. Transmission electron microscopy coupled with energy-dispersive X-ray spectroscopy showed that Pb2+ was adsorbed by n-TiO2 to form NP-Pb complexes in suspension, and these complexes were observed in larval tissues. The bioconcentration of Pb in larvae along with the depuration rates of Pb were higher in the presence of n-TiO2 compared to when n-TiO2 was absent. Exposure to Pb alone induced the expression of the biomarker metallothionein, downregulated neurodevelopment-related genes, and reduced swimming activity of larvae. However, the addition of n-TiO2 to the exposure solution alleviated these effects. The results suggest that n-TiO2 can act as a carrier of Pb to increase its bioconcentration; however, the formation of NP-Pb complexes likely reduces the amount of free Pb2+, thereby reducing toxicity to larvae. |
WOS关键词 | THYROID ENDOCRINE SYSTEM ; TIO2 NANOPARTICLES ; DAPHNIA-MAGNA ; NEURONAL DEVELOPMENT ; OXIDE NANOPARTICLES ; METAL UPTAKE ; BIOACCUMULATION ; EXPOSURE ; EMBRYOS ; CADMIUM |
资助项目 | National Natural Science Foundation of China[21806091] ; National Natural Science Foundation of China[21577168] ; State Key Laboratory of Freshwater Ecology and Biotechnology[2019FBZ03] |
WOS研究方向 | Marine & Freshwater Biology ; Toxicology |
语种 | 英语 |
WOS记录号 | WOS:000486357100016 |
出版者 | ELSEVIER |
资助机构 | National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology ; State Key Laboratory of Freshwater Ecology and Biotechnology |
源URL | [http://ir.ihb.ac.cn/handle/342005/33501] ![]() |
专题 | 水生生物研究所_水环境工程研究中心_期刊论文 |
通讯作者 | Han, Jian; Wu, Hongjuan |
作者单位 | 1.Huazhong Univ Sci & Technol, Sch Environm Sci & Engn, 1037 Luoyu Rd, Wuhan 430074, Hubei, Peoples R China 2.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China 3.Univ Oxford, Environm Change Inst, Oxford OX1 3QY, England |
推荐引用方式 GB/T 7714 | Hu, Shengchao,Han, Jian,Yang, Lihua,et al. Bioconcentration, depuration and toxicity of Pb in the presence of titanium dioxide nanoparticles in zebrafish larvae[J]. AQUATIC TOXICOLOGY,2019,214(1):10. |
APA | Hu, Shengchao.,Han, Jian.,Yang, Lihua.,Li, Sen.,Guo, Yongyong.,...&Wu, Hongjuan.(2019).Bioconcentration, depuration and toxicity of Pb in the presence of titanium dioxide nanoparticles in zebrafish larvae.AQUATIC TOXICOLOGY,214(1),10. |
MLA | Hu, Shengchao,et al."Bioconcentration, depuration and toxicity of Pb in the presence of titanium dioxide nanoparticles in zebrafish larvae".AQUATIC TOXICOLOGY 214.1(2019):10. |
入库方式: OAI收割
来源:水生生物研究所
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