Comparative toxicity of nano-ZnO and bulk ZnO suspensions to zebrafish and the effects of sedimentation, (center dot)OH production and particle dissolution in distilled water
文献类型：期刊论文
| 作者 | Yu, Lin-peng ; Fang, Tao ; Xiong, Dao-wen ; Zhu, Wen-tao ; Sima, Xiao-feng |
| 刊名 | JOURNAL OF ENVIRONMENTAL MONITORING
 |
| 出版日期 | 2011 |
| 卷号 | 13期号:7页码:1975-1982 |
| 关键词 | ZINC-OXIDE NANOPARTICLES OXIDATIVE STRESS DAPHNIA-MAGNA HYDROXYL RADICALS TITANIUM-DIOXIDE CARBON NANOTUBES TIO2 CELLS GROWTH CUO |
| ISSN号 | 1464-0325 |
| 通讯作者 | Fang, T (reprint author), Chinese Acad Sci, Inst Hydrobiol, Wuhan 430072, Hubei, Peoples R China ; fangt@ihb.ac.cn |
| 中文摘要 | With the common application of nanoscale zinc oxide (nZnO) and significant potential for its release directly into aquatic environments, it is urgent to carry out research on ecotoxicological impact of nZnO. The characterization of nZnO, the amount of (center dot)OH in suspensions in the presence of light and the acute toxicity of nZnO and its bulk counterpart suspensions, as well as the acute toxicity of Zn(2+) solution to zebrafish (Danio rerio) at 96 h were studied. It was found that nZnO aggregated into irregular shapes in suspensions, and showed a relationship between its size distribution and concentration. In the presence of light, nZnO suspensions could generate (center dot)OH, the concentration of which increased with time. Although it was generally thought that (center dot)OH played a role in the biotoxicity to zebrafish, similar toxicity was observed for the nZnO and bulk ZnO suspensions (96 h LC(50) 3.969 mg L(-1), 2.525 mg L(-1), respectively). Furthermore, the sedimentation of nZnO and bulk ZnO in suspensions, and the accumulation of Zn in zebrafish were studied. The results showed that dissolved Zn(2+), from nZnO and bulk ZnO in suspensions, were toxic to zebrafish, while the aggregation and sedimentation of nZnO suspensions reduced the toxicity of nZnO. However, Zn(2+) may not be the main source of acute toxicity of nZnO and bulk ZnO to zebrafish. The experimental results highlight the importance of a systematic assessment of toxicity mechanisms of metal oxide nanoparticles (NPs) to determine definitively whether their toxicity is caused by nano-effects. |
| 学科主题 | Chemistry; Environmental Sciences & Ecology |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China[21037004]; Key Project of the National Science and Technology Program[2008ZX07103001] |
| 语种 | 英语 |
| 公开日期 | 2011-11-09 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/16335]  |
| 专题 | 水生生物研究所_水环境工程研究中心_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yu, Lin-peng,Fang, Tao,Xiong, Dao-wen,et al. Comparative toxicity of nano-ZnO and bulk ZnO suspensions to zebrafish and the effects of sedimentation, (center dot)OH production and particle dissolution in distilled water[J]. JOURNAL OF ENVIRONMENTAL MONITORING,2011,13(7):1975-1982. |
| APA | Yu, Lin-peng,Fang, Tao,Xiong, Dao-wen,Zhu, Wen-tao,&Sima, Xiao-feng.(2011).Comparative toxicity of nano-ZnO and bulk ZnO suspensions to zebrafish and the effects of sedimentation, (center dot)OH production and particle dissolution in distilled water.JOURNAL OF ENVIRONMENTAL MONITORING,13(7),1975-1982. |
| MLA | Yu, Lin-peng,et al."Comparative toxicity of nano-ZnO and bulk ZnO suspensions to zebrafish and the effects of sedimentation, (center dot)OH production and particle dissolution in distilled water".JOURNAL OF ENVIRONMENTAL MONITORING 13.7(2011):1975-1982. |
入库方式： OAI收割
来源：水生生物研究所
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