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Quantum dots, lighting up the research and development of nanomedicine
文献类型：期刊论文
| 作者 | Wang, Yunqing ; Chen, Lingxin1
|
| 刊名 | NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE
 |
| 出版日期 | 2011-08-01 |
| 卷号 | 7期号:4页码:385-402 |
| 关键词 | Quantum dots Nanomedicine Fluorescence imaging Multifunctional drug delivery system |
| ISSN号 | 1549-9634 |
| 产权排序 | [Chen, LX] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China; Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai, Peoples R China |
| 通讯作者 | Chen, LX, Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. lxchen@yic.ac.cn |
| 中文摘要 | Quantum dots (QDs) have proven themselves as powerful inorganic fluorescent probes, especially for long term, multiplexed imaging and detection. The newly developed QDs labeling techniques have facilitated the study of drug delivery on the level of living cells and small animals. Moreover, based on QDs and fluorescence imaging system, multifunctional nanocomplex integrated targeting, imaging and therapeutic functionalities have become effective materials for synchronous cancer diagnosis and treatment. In this review, we will summarize the recent advances of QDs in the research of drug delivery system from the following aspects: surface modification strategies of QDs for drug delivery, QDs as drug nanocarriers, QD-labeled drug nanocarriers, QD-based fluorescence resonance energy transfer (FRET) technique for drug release study as well as the development of multifunctional nanomedicines. Possible perspective in this field will also be discussed. From the Clinical Editor: This review discusses the role and significance of quantum dots (QDs) from the following aspects: surface modification strategies of QDs for drug delivery, QDs as drug nanocarriers, QD-labeled drug nanocarriers, QD-based fluorescence resonance energy transfer (FRET) technique for drug release study as well as the development of multifunctional nanomedicines. (C) 2011 Elsevier Inc. All rights reserved. |
| 英文摘要 | Quantum dots (QDs) have proven themselves as powerful inorganic fluorescent probes, especially for long term, multiplexed imaging and detection. The newly developed QDs labeling techniques have facilitated the study of drug delivery on the level of living cells and small animals. Moreover, based on QDs and fluorescence imaging system, multifunctional nanocomplex integrated targeting, imaging and therapeutic functionalities have become effective materials for synchronous cancer diagnosis and treatment. In this review, we will summarize the recent advances of QDs in the research of drug delivery system from the following aspects: surface modification strategies of QDs for drug delivery, QDs as drug nanocarriers, QD-labeled drug nanocarriers, QD-based fluorescence resonance energy transfer (FRET) technique for drug release study as well as the development of multifunctional nanomedicines. Possible perspective in this field will also be discussed. |
| 学科主题 | Science & Technology - Other Topics; Research & Experimental Medicine |
| 研究领域[WOS] | Science & Technology - Other Topics ; Research & Experimental Medicine |
| 关键词[WOS] | FREE POLY(LACTIDE-CO-GLYCOLIDE) NANOPARTICLES ; HYALURONIC-ACID DERIVATIVES ; RESONANCE ENERGY-TRANSFER ; GROWTH-FACTOR RECEPTOR ; TUMOR-CELL UPTAKE ; IN-VIVO ; DRUG-DELIVERY ; LIVING CELLS ; CARBON NANOTUBES ; SIRNA DELIVERY |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China[20975089]; Chinese Academy of Sciences[KZCX2-EW-206]; Department of Science and Technology of Shandong Province of China[2008GG20005005] |
| 语种 | 英语 |
| WOS记录号 | WOS:000293218800003 |
| 公开日期 | 2011-11-11 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/5112]  |
| 专题 | 烟台海岸带研究所_山东省海岸带环境工程技术研究中心 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Yantai 264003, Peoples R China 3.Shandong Prov Key Lab Coastal Zone Environm Proc, Yantai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Yunqing,Chen, Lingxin. Quantum dots, lighting up the research and development of nanomedicine[J]. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE,2011,7(4):385-402. |
| APA | Wang, Yunqing,&Chen, Lingxin.(2011).Quantum dots, lighting up the research and development of nanomedicine.NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE,7(4),385-402. |
| MLA | Wang, Yunqing,et al."Quantum dots, lighting up the research and development of nanomedicine".NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE 7.4(2011):385-402. |
入库方式： OAI收割
来源：烟台海岸带研究所
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