A highly sensitive turn-on fluorescent chemosensor for recognition of Zn(II) ions and its application in live cells imaging
文献类型：期刊论文
| 作者 | Wang, Peng; Wu, Jiang |
| 刊名 | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
 |
| 出版日期 | 2020 |
| 卷号 | 386 |
| 关键词 | Histidine Chemosensor Reversibility Zn(II) ions Cells imaging |
| 英文摘要 | A novel and simple fluorescent chemosensor, DH, was synthesized. As designed, DH displayed excellent selectivity exhibiting a "turn-on" response for Zn2+ over other relevant metal ions based on PET mechanism in 100% aqueous media, and the binding constant of Zn2+ binding to DH was calculated to be 7.27 x 10(8) M-2. Importantly, DH exhibited high sensitivity as a Zn2+ fluorescent chemosensor with a limit of detection (LOD) of 19.25 nM, which is lower than WHO guidelines (76.0 mu M). Moreover, the 2:1 stoichiometry between the chemosensor DH and Zn2+ was verified by Job's plot, fluorescent titration and high resolution mass spectroscopy. In addition, the recognition process of DH toward Zn2+ was chemically reversible and recyclable by adding Na(2)EDTA. Moreover, due to its good biocompatibility and low cytotoxicity, DH was successfully applied to the fluorescence imaging of Zn2+ and Na(2)EDTA in living HK2 cells. |
| 源URL | [http://210.75.249.4/handle/363003/59669]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Wang, Peng,Wu, Jiang. A highly sensitive turn-on fluorescent chemosensor for recognition of Zn(II) ions and its application in live cells imaging[J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,2020,386. |
| APA | Wang, Peng,&Wu, Jiang.(2020).A highly sensitive turn-on fluorescent chemosensor for recognition of Zn(II) ions and its application in live cells imaging.JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,386. |
| MLA | Wang, Peng,et al."A highly sensitive turn-on fluorescent chemosensor for recognition of Zn(II) ions and its application in live cells imaging".JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 386(2020). |
入库方式： OAI收割
来源：西北高原生物研究所
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