Selective imaging of analytes in living cells and zebrafish using a novel peptide-based fluorescence chemosensor with different responses
文献类型：期刊论文
| 作者 | Li, Yongxin; Di, Cuixia; Wu, Jiang; Si, Jing; Zhang, Qianjing; Zhang, Hong; Ge, Yushu; Liu, Dan; Liu, Weisheng |
| 刊名 | MICROCHEMICAL JOURNAL
 |
| 出版日期 | 2019 |
| 卷号 | 150 |
| 关键词 | Peptide backbone Fluorescence chemosensor Cell imaging Zebrafish imaging |
| 英文摘要 | Monitoring and imaging the requirements of heavy metal ions in organisms are very strict, so biologists and chemists wishfully expect powerful probes to achieve. Herein, DnsP has been successfully designed and synthesized using a highly biocompatible and low biotoxic peptide backbone as an ionophore to selectively detect Zn2+ and Cu2+ in aqueous solution in different response modes. In addition, the DnsP-Cu2+ system has high selectivity for H2S and can restore the fluorescence of DnsP for the detection of S2-. Finally, DnsP demonstrated excellent cell permeation and low biological toxicity for biosensing in cellular and zebrafish. Therefore, DnsP represents a prominent peptide fluorescence chemosensor, capable of multifunctional analyte detection and continuous response imaging in environmental and biological systems. |
| 源URL | [http://210.75.249.4/handle/363003/59677]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Li, Yongxin,Di, Cuixia,Wu, Jiang,et al. Selective imaging of analytes in living cells and zebrafish using a novel peptide-based fluorescence chemosensor with different responses[J]. MICROCHEMICAL JOURNAL,2019,150. |
| APA | Li, Yongxin.,Di, Cuixia.,Wu, Jiang.,Si, Jing.,Zhang, Qianjing.,...&Liu, Weisheng.(2019).Selective imaging of analytes in living cells and zebrafish using a novel peptide-based fluorescence chemosensor with different responses.MICROCHEMICAL JOURNAL,150. |
| MLA | Li, Yongxin,et al."Selective imaging of analytes in living cells and zebrafish using a novel peptide-based fluorescence chemosensor with different responses".MICROCHEMICAL JOURNAL 150(2019). |
入库方式： OAI收割
来源：西北高原生物研究所
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