Rapid microwave assisted derivatization of nitrofuran metabolites for analysis in shrimp by high performance liquid chromatography-fluorescence detector
文献类型：期刊论文
| 作者 | Luo, Xianzhu; Yu, Yanxin; Kong, Xiaojian; Wang, Xu; Ji, Zhongyin; Sun, Zhiwei; You, Jinmao
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| 刊名 | MICROCHEMICAL JOURNAL
 |
| 出版日期 | 2019 |
| 卷号 | 150 |
| 关键词 | Microwave-assisted derivatization Nitrofurans metabolites HPLC-FLD 4-(Acridone-10-yl)benzaldehyde Box-Behnken design |
| 英文摘要 | A sensitive analytical method was proposed based on high-performance liquid chromatography with fluorescence detection coupled with microwave-assisted derivatization for the quantitative analysis of nitrofurans metabolites in shrimp samples. A novel derivatization reagent, 4-(acridone-10-yl)benzaldehyde, was synthesized and applied to the derivatization of several common nitrofurans metabolites (semicarbazide, 1-aminohydantoin, 3-amino-2-oxazolidinone, and 3-amino-morpholinomethyl-2-oxazolidinone). The influences of microwave power, irradiation time and temperature on the derivatization efficiency were investigated using Box-Behnken design. Moreover, microwave-assisted derivatization can obtain higher derivatization yields in a shorter period of time. Under the optimized conditions, the derivatization was achieved within 7.2 min. Lower limits of detection were obtained ranging from 0.20 to 0.28 mu g/kg for all nitrofurans metabolites compounds. Satisfactory recoveries were obtained ranging from 90.5 to 103.6%. The developed method was successfully applied to the determination of four nitrofurans metabolites in shrimp. Furthermore, this developed method should offer great potential to the analysis of nitrofurans metabolites in foodstuffs. |
| 源URL | [http://210.75.249.4/handle/363003/59678]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Luo, Xianzhu,Yu, Yanxin,Kong, Xiaojian,et al. Rapid microwave assisted derivatization of nitrofuran metabolites for analysis in shrimp by high performance liquid chromatography-fluorescence detector[J]. MICROCHEMICAL JOURNAL,2019,150. |
| APA | Luo, Xianzhu.,Yu, Yanxin.,Kong, Xiaojian.,Wang, Xu.,Ji, Zhongyin.,...&You, Jinmao.(2019).Rapid microwave assisted derivatization of nitrofuran metabolites for analysis in shrimp by high performance liquid chromatography-fluorescence detector.MICROCHEMICAL JOURNAL,150. |
| MLA | Luo, Xianzhu,et al."Rapid microwave assisted derivatization of nitrofuran metabolites for analysis in shrimp by high performance liquid chromatography-fluorescence detector".MICROCHEMICAL JOURNAL 150(2019). |
入库方式： OAI收割
来源：西北高原生物研究所
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