Highly selective and sensitive peptide-based fluorescent chemosensor for detection of Zinc(II) ions in aqueous medium and living cells
文献类型：期刊论文
| 作者 | Wang, Peng; Wu, Xuehua; Wu, Jiang; Liao, Yunwen |
| 刊名 | JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
 |
| 出版日期 | 2019 |
| 卷号 | 382 |
| 关键词 | Peptide Chemosensor Reversibility Zn(II) ions Cells imaging |
| 英文摘要 | A novel peptide-based chemosensor (L, Dansyl-Asp-His-NH2) has been successfully designed and synthesized. L displayed excellent selectivity in fluorescence detection of Zn2+ over other essential metal ions, with a binding constant value of 4.09 x 10(10) M-2. Further, a Job's plot confirmed the 2:1 stoichiometry of the complex formation between the L and Zn2+ ions. L exhibited a highly-sensitive strong fluorescence "turn-on" effect for Zn2+ in aqueous solution, with a detection limit for Zn2+ calculated at 36.8 nM. Notably, L served as a recyclable chemosensor, which was cyclically controlled by Zn2+ and Na(2)EDTA. Moreover, L exhibited low toxicity in HK2 normal cells, and was then applied to monitor intracellular Zn2+ and Na(2)EDTA in human prostate cancer cells (LNCaP cells). |
| 源URL | [http://210.75.249.4/handle/363003/59716]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Wang, Peng,Wu, Xuehua,Wu, Jiang,et al. Highly selective and sensitive peptide-based fluorescent chemosensor for detection of Zinc(II) ions in aqueous medium and living cells[J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,2019,382. |
| APA | Wang, Peng,Wu, Xuehua,Wu, Jiang,&Liao, Yunwen.(2019).Highly selective and sensitive peptide-based fluorescent chemosensor for detection of Zinc(II) ions in aqueous medium and living cells.JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY,382. |
| MLA | Wang, Peng,et al."Highly selective and sensitive peptide-based fluorescent chemosensor for detection of Zinc(II) ions in aqueous medium and living cells".JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY 382(2019). |
入库方式： OAI收割
来源：西北高原生物研究所
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