Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds
文献类型：期刊论文
| 作者 | Wu, Jiyao; Wang, Jianjin; Yue, Binglin; Fang Xing-tang; Zhang, Chunlei; Ma, Yun; Hu, Linyong ; Bai, Yueyu; Qi, Xingshan; Chen, Hong
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| 刊名 | ANIMAL BIOTECHNOLOGY
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| 出版日期 | 2019 |
| 卷号 | 30期号:3 |
| 关键词 | TRPV1 and TRPA1 SNPs growth traits polymorphism cattle |
| 英文摘要 | The objective of this study was to examine the association of transient receptor potential vanilloid 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1) genes polymorphisms with growth traits in three Chinese cattle breeds (Jiaxian red cattle, Qinchuan cattle and Luxi cattle). Through experiments we identified three single nucleotide polymorphisms (SNPs) in these three cattle breeds TRPV1 and TRPA1 genes using PCR-SSCP, (forced) PCR-RFLP methods. Three of these polymorphisms are all synonymous mutation which includes (NW_003104493.1: 30327 C > T), (NW_003104493.1: 33394 A > G) and (NW_003104493.1: 38471 G > A) are in exons. The other three polymorphisms are located at 3'UTR. Furthermore, we evaluated the haplotype frequency and the statistical analyses indicated that these SNPs of TRPV1 and TRPA1 genes were associated with bovine body height, body length, waist angle width, hucklebone width, cross ministry height, chest qingwidth (p < 0.05) and recommendation height, cannon circumference (p < 0.01) of Qingchuan cattle; body length, waist angle width (p < 0.05) of Jiaxian red cattle; body weight, Body length, cannon circumference, chest circumference (p < 0.05) and body height (p < 0.01) of Luxi cattle. Our result confirms the polymorphisms in the TRPV1 and TRPA1 genes are associated with growth traits that may be used for marker-assisted selection (MAS) in three beef breeds programs. |
| 源URL | [http://210.75.249.4/handle/363003/59750]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Wu, Jiyao,Wang, Jianjin,Yue, Binglin,et al. Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds[J]. ANIMAL BIOTECHNOLOGY,2019,30(3). |
| APA | Wu, Jiyao.,Wang, Jianjin.,Yue, Binglin.,Fang Xing-tang.,Zhang, Chunlei.,...&Chen, Hong.(2019).Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds.ANIMAL BIOTECHNOLOGY,30(3). |
| MLA | Wu, Jiyao,et al."Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds".ANIMAL BIOTECHNOLOGY 30.3(2019). |
入库方式： OAI收割
来源：西北高原生物研究所
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