pH-Dependent Effects of L-Cysteine on Mercury Dissolution of alpha-HgS and beta-HgS
文献类型：期刊论文
| 作者 | Zhang, Ming; Bi, Hongtao; Li, Cen; Du, Yuzhi ; Wei, Lixin
|
| 刊名 | BIOLOGICAL TRACE ELEMENT RESEARCH
 |
| 出版日期 | 2018 |
| 卷号 | 185期号:2 |
| 关键词 | Mercury sulfide L-cysteine Mercury dissolution pH-dependent effects |
| 英文摘要 | Mercury sulfide is an insoluble inorganic mercury compound, and it is the main chemical form in traditional oral mercury-containing medicines. Hg2+ has a high affinity for thiols, and small molecule thiols in the gastrointestinal tract may promote mercury dissolution of mercury sulfide by binding to Hg2+. L-cysteine is the only amino acid that possesses a reducing sulfhydryl group (-SH), out of the 20 amino acids. This study investigates the effect of L-cysteine on mercury dissolution of mercury sulfide at pHs ranging from 1.2 to 7.2. The results showed that L-cysteine had different pH-dependent effects on the mercury dissolution of alpha-HgS and beta-HgS. For alpha-HgS, the dissolved mercury concentration increased from 5.47 +/- 0.97 ng/mL to 12.49 +/- 0.54 ng/mL when the pH rose from 1.2 to 4.2, and decreased to 3.37 +/- 0.70 ng/mL at pH 6.0 and then increased to 9.36 +/- 0.79 ng/mL at pH 7.2. For beta-HgS, the dissolved mercury concentration increased from 151.09 +/- 2.25 ng/mL to 2346.71 +/- 62.62 ng/mL when the pH increased from 1.2 to 7.2. In conclusion, L-Cys was distinctly enhanced upon mercury dissolution of alpha-HgS and beta-HgS with increasing pH. These results may contribute to our understanding of the mercury absorption mechanism of traditional oral mercury-containing medicines. |
| 源URL | [http://210.75.249.4/handle/363003/59956]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Zhang, Ming,Bi, Hongtao,Li, Cen,et al. pH-Dependent Effects of L-Cysteine on Mercury Dissolution of alpha-HgS and beta-HgS[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2018,185(2). |
| APA | Zhang, Ming,Bi, Hongtao,Li, Cen,Du, Yuzhi,&Wei, Lixin.(2018).pH-Dependent Effects of L-Cysteine on Mercury Dissolution of alpha-HgS and beta-HgS.BIOLOGICAL TRACE ELEMENT RESEARCH,185(2). |
| MLA | Zhang, Ming,et al."pH-Dependent Effects of L-Cysteine on Mercury Dissolution of alpha-HgS and beta-HgS".BIOLOGICAL TRACE ELEMENT RESEARCH 185.2(2018). |
入库方式： OAI收割
来源：西北高原生物研究所
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