A Pair of Windmill-Shaped Enantiomers from Lindera aggregata with Activity toward Improvement of Insulin Sensitivity
文献类型：期刊论文
| 作者 | Wang, Fei2,3; Gao, Yuan3; Zhang, Ling2; Bai, Bing2; Hu, Ya Nan1; Dong, Ze Jun2; Zhai, Qi Wei1; Zhu, Hua Jie2; Liu, Ji Kai2 |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2010-07-16 |
| 卷号 | 12期号:14页码:3196-3199 |
| 关键词 | SESQUITERPENE LACTONES OPTICAL-ROTATION WATER EXTRACT STRYCHNIFOLIA ROOT BUTANOLIDES |
| ISSN号 | 1523-7060 |
| 英文摘要 | (+)-Linderaspirone A and (-)-linderaspirone A, a pair of natural windmill-shaped enantiomers, were isolated from the traditional Chinese medicine plant tinders aggregate by HPLC using a chiral column, achieving over 98% ee. Their structures and absolute configurations were determined on the basis of extensive analysis of NMR spectra, crystal X-ray diffraction, and calculation of the optical rotations (OR). They have an unprecedented carbon skeleton and showed significant activity against glucosamine-induced insulin resistance. |
| 学科主题 | Chemistry, Organic |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | SESQUITERPENE LACTONES ; OPTICAL-ROTATION ; WATER EXTRACT ; STRYCHNIFOLIA ; ROOT ; BUTANOLIDES |
| 收录类别 | SCI ; IC |
| 资助信息 | National Basic Research Program of China (973 Program) [2009CB522300]; National Natural Science Foundation of China [30830113]; MOST [2009ZX09501-029, 2009ZX09501-013] |
| 语种 | 英语 |
| WOS记录号 | WOS:000279569600022 |
| 公开日期 | 2012-03-21 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/4286]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.BioBioPha Co Ltd, Kunming 650204, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Nutr Sci, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Fei,Gao, Yuan,Zhang, Ling,et al. A Pair of Windmill-Shaped Enantiomers from Lindera aggregata with Activity toward Improvement of Insulin Sensitivity[J]. ORGANIC LETTERS,2010,12(14):3196-3199. |
| APA | Wang, Fei.,Gao, Yuan.,Zhang, Ling.,Bai, Bing.,Hu, Ya Nan.,...&Liu, Ji Kai.(2010).A Pair of Windmill-Shaped Enantiomers from Lindera aggregata with Activity toward Improvement of Insulin Sensitivity.ORGANIC LETTERS,12(14),3196-3199. |
| MLA | Wang, Fei,et al."A Pair of Windmill-Shaped Enantiomers from Lindera aggregata with Activity toward Improvement of Insulin Sensitivity".ORGANIC LETTERS 12.14(2010):3196-3199. |
入库方式： OAI收割
来源：昆明植物研究所
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