Development of biosensor based on imaging ellipsometry and biomedical applications
文献类型：期刊论文
| 作者 | Jin G(靳刚) ; Meng YH(孟永宏); Liu L(刘丽); Niu Y(牛宇); Chen S(陈涉); Cai Q; Jiang TJ
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| 刊名 | Thin Solid Films
 |
| 出版日期 | 2011 |
| 卷号 | 519期号:9页码:2750-2757 |
| 通讯作者邮箱 | gajin@imech.ac.cn |
| 关键词 | Imaging Ellipsometry Biosensor Protein Microarray Total Internal Reflection Off-Null Ellipsometry Optical Protein-Chip Optimization Visualization |
| ISSN号 | 0040-6090 |
| 产权排序 | [Jin, G; Meng, YH; Liu, L; Niu, Y; Chen, S] Chinese Acad Sci, NML, Inst Mech, Beijing 100190, Peoples R China; [Cai, Q; Jiang, TJ] Chinese Acad Sci, Inst Biophys, Beijing 100101, Peoples R China |
| 通讯作者 | Jin, G (reprint author), Chinese Acad Sci, NML, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China |
| 合作状况 | 国内 |
| 中文摘要 | So far, combined with a microfluidic reactor array system, an engineering system of biosensor based on imaging ellipsometry is installed for biomedical applications, such as antibody screen, hepatitis B markers detection, cancer markers spectrum and virus recognition, etc. Furthermore, the biosensor in total internal reflection (TIR) mode has be improved by a spectroscopic light, optimization settings of polarization and low noise CCD which brings an obvious improvement of 10 time increase in the sensitivity and SNR, and 50 times lower concentration in the detection limit with a throughput of 48 independent channels and the time resolution of 0.04 S. (C) 2010 Elsevier B.V. All rights reserved. |
| 学科主题 | Materials Science; Physics |
| 分类号 | 二类/Q2 |
| 类目[WOS] | Materials Science, Multidisciplinary ; Materials Science, Coatings & Films ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Materials Science ; Physics |
| 关键词[WOS] | OFF-NULL ELLIPSOMETRY ; OPTICAL PROTEIN-CHIP ; OPTIMIZATION ; VISUALIZATION |
| 收录类别 | SCI ; EI |
| 原文出处 | http://dx.doi.org/10.1016/j.tsf.2010.12.175 |
| 语种 | 英语 |
| WOS记录号 | WOS:000289174200040 |
| 公开日期 | 2012-04-01 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/45099]  |
| 专题 | 力学研究所_国家微重力实验室 |
| 推荐引用方式 GB/T 7714 | Jin G,Meng YH,Liu L,et al. Development of biosensor based on imaging ellipsometry and biomedical applications[J]. Thin Solid Films,2011,519(9):2750-2757. |
| APA | Jin G.,Meng YH.,Liu L.,Niu Y.,Chen S.,...&Jiang TJ.(2011).Development of biosensor based on imaging ellipsometry and biomedical applications.Thin Solid Films,519(9),2750-2757. |
| MLA | Jin G,et al."Development of biosensor based on imaging ellipsometry and biomedical applications".Thin Solid Films 519.9(2011):2750-2757. |
入库方式： OAI收割
来源：力学研究所
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