Total internal reflection imaging ellipsometry (TIRIE) biosensor sensitivity improvement with low noise imaging device
文献类型：会议论文
| 作者 | Liu L(刘丽) ; Jin G(靳刚)
|
| 出版日期 | 2011 |
| 会议名称 | Conference on Sensors, Cameras, and Systems for Industrial, Scientific, and Consumer Applications XII |
| 会议日期 | JAN 25-27, 2011 |
| 会议地点 | San Francisco, CA |
| 通讯作者邮箱 | gajin@imech.ac.cn |
| 关键词 | total internal reflection imaging ellipsometry biosensor |
| 卷号 | 7875 |
| 页码 | 78750U |
| 通讯作者 | Jin, G (reprint author), Chinese Acad Sci, NML, Inst Mech, 15 Bei Si Huan W Rd, Beijing 100190, Peoples R China |
| 中文摘要 | The biosensors with properties of real-time, high throughput and label-free are more and more popular recently, in which the biosensor based on the total internal reflection imaging ellipsometry (TIRIE) is a novel imaging detector for protein interaction processes. In previous work, three techniques are introduced to improve the performance of the biosensor including polarization setting optimization, spectroscopic light source application and low noise CCD detector adoption. In this paper, the effect of the low noise CCD detector technology on the sensitivity and detection limit improvement is analyzed. An obvious improvement of 10 time increase in the sensitivity and SNR, and 50 times lower concentration in the detection limit is obtained by optimization. |
| 收录类别 | CPCI |
| 产权排序 | Chinese Acad Sci, NML, Inst Mech, Beijing 100190, Peoples R China |
| 会议网址 | http://dx.doi.org/10.1117/12.871978 |
| 会议录 | SENSORS, CAMERAS, AND SYSTEMS FOR INDUSTRIAL, SCIENTIFIC, AND CONSUMER APPLICATIONS XII
 |
| 会议录出版者 | SPIE-INT SOC OPTICAL ENGINEERING |
| 学科主题 | Optics |
| 会议录出版地 | 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA |
| 语种 | 英语 |
| ISSN号 | 0277-786X |
| ISBN号 | 978-0-8194-8412-3 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/45327]  |
| 专题 | 力学研究所_国家微重力实验室 |
| 推荐引用方式 GB/T 7714 | Liu L,Jin G. Total internal reflection imaging ellipsometry (TIRIE) biosensor sensitivity improvement with low noise imaging device[C]. 见:Conference on Sensors, Cameras, and Systems for Industrial, Scientific, and Consumer Applications XII. San Francisco, CA. JAN 25-27, 2011.http://dx.doi.org/10.1117/12.871978. |
入库方式： OAI收割
来源：力学研究所
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