Mono-dispersed bioactive glass nanospheres: Preparation and effects on biomechanics of mammalian cells
文献类型：期刊论文
| 作者 | Hong ZK ; Luz GM ; Hampel PJ ; Jin MS ; Liu AX ; Chen XS ; Mano JF |
| 刊名 | journal of biomedical materials research part a
 |
| 出版日期 | 2010 |
| 卷号 | 95a期号:3页码:747-754 |
| 关键词 | MESENCHYMAL STEM-CELLS IN-VITRO CHARACTERIZATION SOL-GEL METHOD CERAMIC NANOPARTICLES HEMOSTATIC ACTIVITY SYSTEM COMPOSITES MECHANICS PARTICLES BIOGLASS |
| ISSN号 | 1549-3296 |
| 通讯作者 | hong zk |
| 中文摘要 | mono-dispersed sio2-cao bioactive glass nanospheres (bgns) were prepared by a two step sol-gel method in the absence of surfactant. the size of bgns ranged from 200 to 350 nm in diameter and exhibited a rough surface texture. in vitro biomineralization tests showed that bgns could rapidly induce the deposition of an apatite layer in simulated body fluid (sew). the effect of bioactive glass on the biomechanical properties of various mammalian cells was first reported in this paper. atomic force microscopy (afm) was used for measuring the biomechanical properties of mammalian cells. the result showed that bgns-medium could significantly decrease the plasma membrane stiffness of bone marrow stem cells (bmscs) by similar to 50% and stimulate bmscs spreading. the effect of bgns on biomechanical properties of bovine aortic endothelial cells (baecs) was opposite to that on bmscs. bgns increased the baecs' stiffness and stimulated the elongation of endothelial cells and the formation of endothelial networks, which might potentially facilitate the vascularization of implanted bgns-based biomaterials in tissue engineering as a scaffold or as an injectable system. (c) 2010 wiley periodicals, inc. j biomed mater res part a: 95a: 747-754, 2010. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000283959800011 |
| 公开日期 | 2012-04-25 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/43299]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Hong ZK,Luz GM,Hampel PJ,et al. Mono-dispersed bioactive glass nanospheres: Preparation and effects on biomechanics of mammalian cells[J]. journal of biomedical materials research part a,2010,95a(3):747-754. |
| APA | Hong ZK.,Luz GM.,Hampel PJ.,Jin MS.,Liu AX.,...&Mano JF.(2010).Mono-dispersed bioactive glass nanospheres: Preparation and effects on biomechanics of mammalian cells.journal of biomedical materials research part a,95a(3),747-754. |
| MLA | Hong ZK,et al."Mono-dispersed bioactive glass nanospheres: Preparation and effects on biomechanics of mammalian cells".journal of biomedical materials research part a 95a.3(2010):747-754. |
入库方式： OAI收割
来源：长春应用化学研究所
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