HPLC/ESI-MSn and ESI-MS studies on the Aconitum alkaloids in three Chinese medicinal herbs
文献类型：期刊论文
| 作者 | Liu WL ; Pi ZF ; Wang XY ; Song FR ; Liu SY |
| 刊名 | journal of separation science
 |
| 出版日期 | 2010 |
| 卷号 | 33期号:17-18页码:2898-2906 |
| 关键词 | IONIZATION MASS-SPECTROMETRY NORDITERPENOID ALKALOIDS DITERPENOID ALKALOIDS CAPILLARY-ELECTROPHORESIS LIQUID-CHROMATOGRAPHY QUANTITATIVE-ANALYSIS ROOTS MESACONITINE |
| ISSN号 | 1615-9306 |
| 通讯作者 | liu sy |
| 中文摘要 | aconitum lipo-alkaloids (ldas) peaks in the previous hplc studies have shown overlapping behavior, making it impossible to identify the total retention behavior of ldas. the structural diversity of ldas in radix aconiti, radix aconiti kusnezoffii and radix aconiti lateralis preparata makes it difficult to synthesize and quantify each of them. therefore, this study has been devoted to develop a hplc/esi-msn method with good resolution of aconitum alkaloids especially ldas and then set up a fast esi-ms sim method to quantify the total contents of specific skeleton ldas in the three herbs via in-source cid and the capability of mass separation. as a result, the retention behavior of ldas was summarized based on an optimized chromatographic separation; 32 alkaloids from the three herbs of aconitum genus were separated and identified according to their fragmentation pathways by using hplc/esi-msn. in addition, a fast quantitative analysis esi-ms sim method was successfully applied to the quantification of the total contents of specific skeleton ldas in the three herbs. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000282612900043 |
| 公开日期 | 2012-04-25 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/43383]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Liu WL,Pi ZF,Wang XY,et al. HPLC/ESI-MSn and ESI-MS studies on the Aconitum alkaloids in three Chinese medicinal herbs[J]. journal of separation science,2010,33(17-18):2898-2906. |
| APA | Liu WL,Pi ZF,Wang XY,Song FR,&Liu SY.(2010).HPLC/ESI-MSn and ESI-MS studies on the Aconitum alkaloids in three Chinese medicinal herbs.journal of separation science,33(17-18),2898-2906. |
| MLA | Liu WL,et al."HPLC/ESI-MSn and ESI-MS studies on the Aconitum alkaloids in three Chinese medicinal herbs".journal of separation science 33.17-18(2010):2898-2906. |
入库方式： OAI收割
来源：长春应用化学研究所
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