中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system

文献类型:期刊论文

作者Pu F ; Wang CY ; Hu D ; Huang ZZ ; Ren JS ; Wang S ; Qu XG
刊名molecular biosystems
出版日期2010
卷号6期号:10页码:1928-1932
关键词WALLED CARBON NANOTUBES G-QUADRUPLEX DNA CONJUGATED POLYMERS I-MOTIF GOLD-NANOPARTICLE DRUG DESIGN SENSORS CONSTRUCTS COMPLEXES THROMBIN
ISSN号1742-206x
通讯作者ren js
中文摘要a conceptually new class of telomere dna/conjugated polymer system has been constructed to enable sensing of ph changes and create robust logic gates capable of multiplex logic operations. it combines the advantages of quadruplex-duplex conversion and efficient energy transfer from the polymer to the dna binding molecule. the system is simple in design, fast in operation, and allows the detection of ph changes with high accuracy and sensitivity. in addition, the approach could be adopted for the investigation of other biomolecular conformational changes upon binding to their targets. more importantly, the present logic operations showed advantages over other nucleic acid-based logic gates: (1) the system does not require any cp modification or oligonucleotide labeling, which offers the advantages of simplicity and cost efficiency. (2) the reversibility of the switch makes the logic gates feasible to realize system reset. (3) the system could be implemented to perform multiple logic functions by using distinct input signals.
收录类别SCI收录期刊论文
语种英语
WOS记录号WOS:000281772300025
公开日期2012-04-25
源URL[http://ir.ciac.jl.cn/handle/322003/43443]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式
GB/T 7714
Pu F,Wang CY,Hu D,et al. Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system[J]. molecular biosystems,2010,6(10):1928-1932.
APA Pu F.,Wang CY.,Hu D.,Huang ZZ.,Ren JS.,...&Qu XG.(2010).Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system.molecular biosystems,6(10),1928-1932.
MLA Pu F,et al."Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system".molecular biosystems 6.10(2010):1928-1932.

入库方式: OAI收割

来源:长春应用化学研究所

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