Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system
文献类型:期刊论文
作者 | Pu F ; Wang CY ; Hu D ; Huang ZZ ; Ren JS ; Wang S ; Qu XG |
刊名 | molecular biosystems
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出版日期 | 2010 |
卷号 | 6期号:10页码:1928-1932 |
关键词 | WALLED CARBON NANOTUBES G-QUADRUPLEX DNA CONJUGATED POLYMERS I-MOTIF GOLD-NANOPARTICLE DRUG DESIGN SENSORS CONSTRUCTS COMPLEXES THROMBIN |
ISSN号 | 1742-206x |
通讯作者 | ren js |
中文摘要 | a conceptually new class of telomere dna/conjugated polymer system has been constructed to enable sensing of ph changes and create robust logic gates capable of multiplex logic operations. it combines the advantages of quadruplex-duplex conversion and efficient energy transfer from the polymer to the dna binding molecule. the system is simple in design, fast in operation, and allows the detection of ph changes with high accuracy and sensitivity. in addition, the approach could be adopted for the investigation of other biomolecular conformational changes upon binding to their targets. more importantly, the present logic operations showed advantages over other nucleic acid-based logic gates: (1) the system does not require any cp modification or oligonucleotide labeling, which offers the advantages of simplicity and cost efficiency. (2) the reversibility of the switch makes the logic gates feasible to realize system reset. (3) the system could be implemented to perform multiple logic functions by using distinct input signals. |
收录类别 | SCI收录期刊论文 |
语种 | 英语 |
WOS记录号 | WOS:000281772300025 |
公开日期 | 2012-04-25 |
源URL | [http://ir.ciac.jl.cn/handle/322003/43443] ![]() |
专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
推荐引用方式 GB/T 7714 | Pu F,Wang CY,Hu D,et al. Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system[J]. molecular biosystems,2010,6(10):1928-1932. |
APA | Pu F.,Wang CY.,Hu D.,Huang ZZ.,Ren JS.,...&Qu XG.(2010).Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system.molecular biosystems,6(10),1928-1932. |
MLA | Pu F,et al."Logic gates and pH sensing devices based on a supramolecular telomere DNA/conjugated polymer system".molecular biosystems 6.10(2010):1928-1932. |
入库方式: OAI收割
来源:长春应用化学研究所
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