Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases
文献类型：期刊论文
| 作者 | Xu, Wenyan1,2,3; Li, Liling2; Du, Liangcheng1; Tan, Ninghua2 |
| 刊名 | ACTA BIOCHIMICA ET BIOPHYSICA SINICA
 |
| 出版日期 | 2011-10-01 |
| 卷号 | 43期号:10页码:757-762 |
| 关键词 | ribosomal peptide cyclopeptides non-ribosomal peptide synthetase cyclization mechanism |
| ISSN号 | 1672-9145 |
| 通讯作者 | Du, LC (reprint author), Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA |
| 英文摘要 | An increasing number of cyclopeptides have been discovered as products of ribosomal synthetic pathway. The biosynthetic study of these cyclopeptides has revealed interesting new mechanisms for cyclization. This review highlighted the recent discoveries in cyclization mechanisms for cyclopeptides synthesized independently of non-ribosomal peptide synthetases, including endopeptidase-catalyzed cyclization, intein-mediated cyclization, and peptide synthetase-catalyzed cyclization. This information may help to design hybrid ribosomal and non-ribosomal biosynthetic systems to produce novel cyclopeptides with various bioactivities. |
| 学科主题 | Biochemistry & Molecular Biology; Biophysics |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | POLYPEPTIDE KALATA B1 ; CIRCULAR PROTEINS ; NATURAL-PRODUCTS ; POSTTRANSLATIONAL MODIFICATION ; THIOESTERASE DOMAINS ; ACYCLIC PERMUTANTS ; CYCLIC-PEPTIDES ; CYSTINE KNOT ; BIOSYNTHESIS ; LIBRARIES |
| 收录类别 | SCI |
| 资助信息 | National Natural Science Foundation of China[30725048, U1032602, 91013002]; Chinese Academy of Sciences[KSCX2-YW-R-177]; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences; Nebraska Research Council; National Institute of Health of USA[RR015468-01]; China Scholarship Council |
| 语种 | 英语 |
| WOS记录号 | WOS:000295411300002 |
| 公开日期 | 2012-04-10 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/5373]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Wenyan,Li, Liling,Du, Liangcheng,et al. Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2011,43(10):757-762. |
| APA | Xu, Wenyan,Li, Liling,Du, Liangcheng,&Tan, Ninghua.(2011).Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,43(10),757-762. |
| MLA | Xu, Wenyan,et al."Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 43.10(2011):757-762. |
入库方式： OAI收割
来源：昆明植物研究所
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