Isolation and Identification of Compounds Responsible for Antioxidant Capacity of Euryale ferox Seeds
文献类型：期刊论文
| 作者 | Song, Chang-Wei1; Wang, Shu-Mei1,3; Zhou, Li-Li2; Hou, Fan-Fan2; Wang, Kai-Jin4; Han, Quan-Bin5; Li, Ning4; Cheng, Yong-Xian1 |
| 刊名 | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
 |
| 出版日期 | 2011-02-23 |
| 卷号 | 59期号:4页码:1199-1204 |
| 关键词 | Euryale ferox Nymphaeaceae lignans antioxidant activity |
| ISSN号 | 0021-8561 |
| 通讯作者 | Cheng, YX (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China |
| 英文摘要 | Euryale ferox seed is consumed medicinally or for food in China. The present study revealed it to contain significant antioxidant activity, which may be associated with its medical applications as a proteinuria inhibitor of diabetic nephropathy. This; study resulted in the identification of 3 new sesquineolignans, named euryalins A-C (1-3), and 16 known compounds, which were I all first isolated from this plant apart from 5,7,4-trihydroxy-flavanone. The antioxidant potential of the partial isolates was evaluated using the DPPH radical scavenging assay and mesangial cellular assay. Compounds 2, rel-(2 alpha,3 beta)-7-O-methylcedrusin (4), syringylglycerol-8-O-4-(sinapyl alcohol) ether (5), and (+)-syringaresinol (7) were found to be most active on DPPH assay, whereas compounds 2, 4, 7, (1R,2R,5R,6S)-2-(3,4-dimethoxyphenyl)-6-(3,4-dihydroxyphenyl)-3,7-dioxabicydo[3.3.0]octane, and buddlenol E could significantly inhibit high glucose-stimulated reactive oxygen species production in mesangial cells. The results suggested that E. ferox seed could be considered as an excellent source of natural antioxidants and is useful in the prevention of diabetic nephropathy. |
| 学科主题 | Agriculture; Chemistry; Food Science & Technology |
| 类目[WOS] | Agriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology |
| 研究领域[WOS] | Agriculture ; Chemistry ; Food Science & Technology |
| 关键词[WOS] | DIABETIC-NEPHROPATHY ; CONSTITUENTS ; INHIBITION ; MECHANISM ; CELLS |
| 收录类别 | SCI ; IC |
| 资助信息 | Ministry of Science; Technology of China[2008ZX09401-004]; State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources; "Talent Scholarship for the Youth of Yunnan"[2007PY01-48] |
| 语种 | 英语 |
| WOS记录号 | WOS:000287297100021 |
| 公开日期 | 2012-04-10 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/5495]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 2.So Med Univ, Nanfang Hosp, Div Nephrol, Key Lab Organ Failure Res,Educ Minist, Guangzhou 510515, Guangdong, Peoples R China 3.Guangdong Pharmaceut Univ, Coll Chinese Med, Guangzhou 510006, Guangdong, Peoples R China 4.Anhui Univ, Sch Life Sci, Anhui 230039, Peoples R China 5.Chinese Univ Hong Kong, Inst Chinese Med, Hong Kong, Hong Kong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Chang-Wei,Wang, Shu-Mei,Zhou, Li-Li,et al. Isolation and Identification of Compounds Responsible for Antioxidant Capacity of Euryale ferox Seeds[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2011,59(4):1199-1204. |
| APA | Song, Chang-Wei.,Wang, Shu-Mei.,Zhou, Li-Li.,Hou, Fan-Fan.,Wang, Kai-Jin.,...&Cheng, Yong-Xian.(2011).Isolation and Identification of Compounds Responsible for Antioxidant Capacity of Euryale ferox Seeds.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,59(4),1199-1204. |
| MLA | Song, Chang-Wei,et al."Isolation and Identification of Compounds Responsible for Antioxidant Capacity of Euryale ferox Seeds".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 59.4(2011):1199-1204. |
入库方式： OAI收割
来源：昆明植物研究所
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