Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi
文献类型：期刊论文
| 作者 | Hu, Zhuo1; Zhan, Rui2,3; Du, Xue2; Su, Jia2; Li, Xiao-Nian2; Yang, Jian-Hong2; Zhang, Hai-Bo2; Li, Yan2 ; Sun, Han-Dong2; Li, Gan-Peng1
|
| 刊名 | CHEMICAL & PHARMACEUTICAL BULLETIN
 |
| 出版日期 | 2011-12-01 |
| 卷号 | 59期号:12页码:1562-1566 |
| 关键词 | Isodon henryi diterpenoid isodonhenrin |
| ISSN号 | 0009-2363 |
| 通讯作者 | Li, GP (reprint author), Yunnan Nationalities Univ, Coll Chem & Biotechnol, Kunming 650031, Peoples R China |
| 英文摘要 | Five new ent-kaurane diterpenoids, isodonhenrins A-E (1-5), together with thirteen known ones were isolated from the aerial parts of Isodon henryi. Their structures were identified by means of extensive spectroscopic analysis, and the absolute configurations of 1 were determined by single-crystal X-ray diffraction. Most of the diterpenoids were evaluated for their cytotoxicity against HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines. Compound 17 showed significant inhibitory effects on five cell lines, and compounds 6, 9, 10, 11, 12 and 16 exhibited selective activity. |
| 学科主题 | Pharmacology & Pharmacy; Chemistry |
| 类目[WOS] | Chemistry, Medicinal ; Chemistry, Multidisciplinary ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy ; Chemistry |
| 关键词[WOS] | CONSTITUENTS |
| 收录类别 | SCI ; IC |
| 资助信息 | NSFC-Joint Foundation of Yunnan Province[U0832602]; Major State Basic Research Development Program of China[2009CB522300, 2009CB940900]; Science and Technology Program of Yunnan Province[2008IF010, 2008CD162]; NSFC[81172939]; Major Direction Projection Foundation[2010KIBA05] |
| 语种 | 英语 |
| WOS记录号 | WOS:000297392300020 |
| 公开日期 | 2012-04-10 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/5535]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Yunnan Nationalities Univ, Coll Chem & Biotechnol, Kunming 650031, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Zhuo,Zhan, Rui,Du, Xue,et al. Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi[J]. CHEMICAL & PHARMACEUTICAL BULLETIN,2011,59(12):1562-1566. |
| APA | Hu, Zhuo.,Zhan, Rui.,Du, Xue.,Su, Jia.,Li, Xiao-Nian.,...&Pu, Jian-Xin.(2011).Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi.CHEMICAL & PHARMACEUTICAL BULLETIN,59(12),1562-1566. |
| MLA | Hu, Zhuo,et al."Cytotoxic ent-Kaurane Diterpenoids from Isodon henryi".CHEMICAL & PHARMACEUTICAL BULLETIN 59.12(2011):1562-1566. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。