Taccasubosides A-D, four new steroidal glycosides from Tacca subflabellata
文献类型：期刊论文
| 作者 | Li, Lei1,2; Ni, Wei1; Li, Xing-Rao1; Hua, Yan2; Fang, Ping-Lei1; Kong, Ling-Mei1; Pan, Li-Li1; Li, Yan1 ; Chen, Chang-Xiang1; Liu, Hai-Yang1
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| 刊名 | STEROIDS
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| 出版日期 | 2011-09-01 |
| 卷号 | 76期号:10-11页码:1037-1042 |
| 关键词 | Tacca subflabellata Taccaceae Taccasubosides A-D Cytotoxic activity |
| ISSN号 | 0039-128X |
| 通讯作者 | Liu, HY (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, 132 Lanhei Rd, Kunming 650204, Yunnan, Peoples R China |
| 英文摘要 | By analyzing the steroidal content of fresh whole plants of Tacca subflabellata (Taccaceae), we isolated one sapogenin and eight glycosides with four kinds of steroidal skeletons including four new glycosides, named taccasubosides A-D (1-4), together with five known compounds. Among them, compound 1 is the first pentacyclic sterol glycoside with 6-6-6-5-6 fused rings. The structures of 1-4 were elucidated on the basis of extensive spectroscopic analysis, including that of 2D NMR data, and the results of acidic hydrolysis. The cytotoxicity of the selected steroidal glycosides (1-4, 8, and 9) was evaluated in vitro against five human cancer cell lines. Compound 9 showed significant inhibitory activity against all five cell lines. (C) 2011 Elsevier Inc. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology; Endocrinology & Metabolism |
| 类目[WOS] | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 关键词[WOS] | SPIROSTANOL SAPONINS ; PENTACYCLIC STEROIDS ; CYTOTOXIC ACTIVITY ; TACCALONOLIDE-A ; PLANTAGINEA ; CHANTRIERI ; RHIZOMES ; GLUCOSIDES ; ROOTS |
| 收录类别 | SCI ; IC |
| 资助信息 | Natural Science Foundation of Yunnan Province[2007C094M]; Young Academic and Technical Leader Raising Foundation of Yunnan Province[2008PY066] |
| 语种 | 英语 |
| WOS记录号 | WOS:000294074700013 |
| 公开日期 | 2012-04-10 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/5553]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China 2.SW Forestry Univ, Fac Nat Resources, Kunming 650224, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Lei,Ni, Wei,Li, Xing-Rao,et al. Taccasubosides A-D, four new steroidal glycosides from Tacca subflabellata[J]. STEROIDS,2011,76(10-11):1037-1042. |
| APA | Li, Lei.,Ni, Wei.,Li, Xing-Rao.,Hua, Yan.,Fang, Ping-Lei.,...&Liu, Hai-Yang.(2011).Taccasubosides A-D, four new steroidal glycosides from Tacca subflabellata.STEROIDS,76(10-11),1037-1042. |
| MLA | Li, Lei,et al."Taccasubosides A-D, four new steroidal glycosides from Tacca subflabellata".STEROIDS 76.10-11(2011):1037-1042. |
入库方式： OAI收割
来源：昆明植物研究所
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